ArticleJournal of biomedicine & biotechnology2001
Genomic Regions That Underlie Soybean Seed Isoflavone Content.
Article in Journal of biomedicine & biotechnology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 102 citations in OpenAlex.
- Identification of Genes Responsible for the Synthesis of Glycitein Isoflavones in Soybean Seeds.Plants (Basel, Switzerland) · 2024Article
- Soybean genetics, genomics, and breeding for improving nutritional value and reducing antinutritional traits in food and feed.The plant genome · 2023Review
- QTL mapping reveals key factors related to the isoflavone contents and agronomic traits of soybean (Glycine max).BMC plant biology · 2023Article
- Single-base deletion inBreeding science · 2020Article
- Identification and characterization of a major QTL underlying soybean isoflavone malonylglycitin content.Breeding science · 2019Article
- Is Chickpea a Potential Substitute for Soybean? Phenolic Bioactives and Potential Health Benefits.International journal of molecular sciences · 2019Review
- Fine-mapping of QTLs for individual and total isoflavone content in soybean (Glycine max L.) using a high-density genetic map.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Exploiting Phenylpropanoid Derivatives to Enhance the Nutraceutical Values of Cereals and Legumes.Frontiers in plant science · 2016Review
- Mapping isoflavone QTL with main, epistatic and QTL × environment effects in recombinant inbred lines of soybean.PloS one · 2015Article
- Article
- Expression quantitative trait loci infer the regulation of isoflavone accumulation in soybean (Glycine max L. Merr.) seed.BMC genomics · 2014Article
- Quantitative trait loci analysis of individual and total isoflavone contents in soybean seeds.Journal of genetics · 2014Article
- Differential effects of short term feeding of a soy protein isolate diet and estrogen treatment on bone in the pre-pubertal rat.PloS one · 2012Article
- Major locus and other novel additive and epistatic loci involved in modulation of isoflavone concentration in soybean seeds.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2011Article
- Soybean cyst nematode resistance in soybean is independent of the Rhg4 locus LRR-RLK gene.Functional & integrative genomics · 2011Article
- Genetic control of soybean seed isoflavone content: importance of statistical model and epistasis in complex traits.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2009Article
- Identification of QTL underlying isoflavone contents in soybean seeds among multiple environments.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2009Article
- Soybean genomics: Developments through the use of cultivar "Forrest".International journal of plant genomics · 2008Article
- The development of BAC-end sequence-based microsatellite markers and placement in the physical and genetic maps of soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2007Article
- An updated 'Essex' by 'Forrest' linkage map and first composite interval map of QTL underlying six soybean traits.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2006Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soy products contain isoflavones (genistein, daidzein, and glycitein) that display biological effects when ingested by humans and animals, these effects are species, dose and age dependent. Therefore, the content and quality of isoflavones in soybeans is a key to their biological effect. Our objective was to identify loci that underlie isoflavone content in soybean seeds. The study involved 100 recombinant inbred lines (RIL) from the cross of 'Essex' by 'Forrest,' two cultivars that contrast for isoflavone content. Isoflavone content of seeds from each RIL was determined by high performance liquid chromatography (HPLC). The distribution of isoflavone content was continuous and unimodal. The heritability estimates on a line mean basis were 79% for daidzein, 22% for genistein, and 88% for glycitein. Isoflavone content of soybean seeds was compared against 150 polymorphic DNA markers in a one-way analysis of variance. Four genomic regions were found to be significantly associated with the isoflavone content of soybean seeds across both locations and years. Molecular linkage group B1 contained a major QTL underlying glycitein content (P = 0.0001, R(2) = 50.2%), linkage group N contained a QTL for glycitein (P = 0.0033, R(2) = 11.1%) and a QTL for daidzein (P = 0.0023, R(2) = 10.3%) and linkage group A1 contained a QTL for daidzein (P = 0.0081, R(2) = 9.6%). Selection for these chromosomal regions in a marker assisted selection program will allow for the manipulation of amounts and profiles of isoflavones (genistein, daidzein, and glycitein) content of soybean seeds. In addition, tightly linked markers can be used in map based cloning of genes associated with isoflavone content.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.