ArticleJournal of biomedicine & biotechnology2002
Werner Syndrome.
Article in Journal of biomedicine & biotechnology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Novel Homozygous Variants in CIDEC and WRN in a Young Female with Lipodystrophy and Thyroid Cancer.International journal of molecular sciences · 2026Article
- Emerging strategies, applications and challenges of targeting NADNature aging · 2025Review
- A Case Report Depicting a Rare Neurosurgical Disease: Aggressive Meningiomatosis.Journal of clinical medicine · 2025Article
- Rare Germline Variants in DNA Repair Genes Detected inCancers · 2024Article
- Skin cancer-associated genodermatoses in skin of color patients: a review.Archives of dermatological research · 2024Review
- Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells.Cell & bioscience · 2022Article
- Article
- Telomerase expression marks transitional growth-associated skeletal progenitor/stem cells.Stem cells (Dayton, Ohio) · 2021Article
- Human pluripotent stem cell-based models suggest preadipocyte senescence as a possible cause of metabolic complications of Werner and Bloom Syndromes.Scientific reports · 2020Article
- SIRT6, a Mammalian Deacylase with Multitasking Abilities.Physiological reviews · 2020Review
- Review
- DNA double strand break repair, aging and the chromatin connection.Mutation research · 2016Review
- E2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution.Cell death and differentiation · 2015Article
- Acetylation of Werner syndrome protein (WRN): relationships with DNA damage, DNA replication and DNA metabolic activities.Biogerontology · 2014Article
- Telomerase protects werner syndrome lineage-specific stem cells from premature aging.Stem cell reports · 2014Article
- Aging genetics and aging.Aging and disease · 2011Article
- Werner syndrome as a hereditary risk factor for exocrine pancreatic cancer: potential role of WRN in pancreatic tumorigenesis and patient-tailored therapy.Cancer biology & therapy · 2010Article
- Is schizophrenia a syndrome of accelerated aging?Schizophrenia bulletin · 2008Review
- Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway.The Journal of cell biology · 2008Article
- Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Werner syndrome is a premature aging disease caused by the mutation in the WRN gene. The cloning and characterization of the WRN gene and its product allows investigators to study the disease and the human aging process at molecular level. This review summarizes the recent progresses on various aspects of the WRN research including functional analysis of the protein, interactive cloning, complexes formation, mouse models, and SNPs (single nucleotide polymorphisms). These in depth investigations have greatly advanced our understanding of the disease and elucidated future research direction for Werner syndrome and the human aging process.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.