ArticleJournal of bacteriology2003
Function of oxygen resistance proteins in the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris hildenborough.
Article in Journal of bacteriology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 100 citations in OpenAlex.
- Growth of sulfate-reducing Desulfobacterota and Bacillota at periodic oxygen stress of 50% air-OMicrobiome · 2024Article
- Article
- When anaerobes encounter oxygen: mechanisms of oxygen toxicity, tolerance and defence.Nature reviews. Microbiology · 2021Review
- Organohalide-respiring Desulfoluna species isolated from marine environments.The ISME journal · 2020Article
- Chemical Warfare at the Microorganismal Level: A Closer Look at the Superoxide Dismutase Enzymes of Pathogens.ACS infectious diseases · 2018Review
- The Dynamic Distribution of Small-Tail Han Sheep Microbiota across Different Intestinal Segments.Frontiers in microbiology · 2018Article
- Hydrogen Dynamics in Cyanobacteria Dominated Microbial Mats Measured by Novel Combined HFrontiers in microbiology · 2017Article
- Response of germ-free mice to colonization with O. formigenes and altered Schaedler flora.Applied and environmental microbiology · 2016Article
- Changing microspatial patterns of sulfate-reducing microorganisms (SRM) during cycling of marine stromatolite mats.International journal of molecular sciences · 2014Article
- The chemical composition of endotoxin isolated from intestinal strain of Desulfovibrio desulfuricans.TheScientificWorldJournal · 2012Article
- How sulphate-reducing microorganisms cope with stress: lessons from systems biology.Nature reviews. Microbiology · 2011Review
- Study of the thiol/disulfide redox systems of the anaerobe Desulfovibrio vulgaris points out pyruvate:ferredoxin oxidoreductase as a new target for thioredoxin 1.The Journal of biological chemistry · 2011Article
- Genome sequence of Desulfobacterium autotrophicum HRM2, a marine sulfate reducer oxidizing organic carbon completely to carbon dioxide.Environmental microbiology · 2009Article
- Pathway for H2O2 and O2 detoxification in Clostridium acetobutylicum.Microbiology (Reading, England) · 2009Article
- Molecular analysis of the spatio-temporal distribution of sulfate-reducing bacteria (SRB) in Camargue (France) hypersaline microbial mat.Microbial ecology · 2008Article
- Superoxide reduction by Nanoarchaeum equitans neelaredoxin, an enzyme lacking the highly conserved glutamate iron ligand.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2008Article
- Multiple superoxide dismutases in Agrobacterium tumefaciens: functional analysis, gene regulation, and influence on tumorigenesis.Journal of bacteriology · 2007Article
- The archaeon Methanosarcina acetivorans contains a protein disulfide reductase with an iron-sulfur cluster.Journal of bacteriology · 2007Article
- Cell-wide responses to low-oxygen exposure in Desulfovibrio vulgaris Hildenborough.Journal of bacteriology · 2007Article
- Superoxide reduction by Archaeoglobus fulgidus desulfoferrodoxin: comparison with neelaredoxin.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2007Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two mutant strains of Desulfovibrio vulgaris Hildenborough lacking either the sod gene for periplasmic superoxide dismutase or the rbr gene for rubrerythrin, a cytoplasmic hydrogen peroxide (H(2)O(2)) reductase, were constructed. Their resistance to oxidative stress was compared to that of the wild-type and of a sor mutant lacking the gene for the cytoplasmic superoxide reductase. The sor mutant was more sensitive to exposure to air or to internally or externally generated superoxide than was the sod mutant, which was in turn more sensitive than the wild-type strain. No obvious oxidative stress phenotype was found for the rbr mutant, indicating that H(2)O(2) resistance may also be conferred by two other rbr genes in the D. vulgaris genome. Inhibition of Sod activity by azide and H(2)O(2), but not by cyanide, indicated it to be an iron-containing Sod. The positions of Fe-Sod and Sor were mapped by two-dimensional gel electrophoresis (2DE). A strong decrease of Sor in continuously aerated cells, indicated by 2DE, may be a critical factor in causing cell death of D. vulgaris. Thus, Sor plays a key role in oxygen defense of D. vulgaris under fully aerobic conditions, when superoxide is generated mostly in the cytoplasm. Fe-Sod may be more important under microaerophilic conditions, when the periplasm contains oxygen-sensitive, superoxide-producing targets.
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