ReviewOncogene2002
Photolyase/cryptochrome blue-light photoreceptors use photon energy to repair DNA and reset the circadian clock.
Review in Oncogene, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 127 citations in OpenAlex.
- The roles of Cryptochrome-1: the circadian clock as a control point in cancer therapy.Journal of translational medicine · 2025Review
- A one-day journey to the suburbs: circadian clock in the Drosophila visual system.The FEBS journal · 2025Review
- The physiological role of TRP channels in sleep and circadian rhythm.Journal of cellular and molecular medicine · 2024Review
- Inhibitors of riboflavin biosynthetic pathway enzymes as potential antibacterial drugs.Frontiers in molecular biosciences · 2023Review
- Nucleotide Variation inFrontiers in physiology · 2022Article
- Chronobiology Meets Quantum Biology: A New Paradigm Overlooking the Horizon?Frontiers in physiology · 2022Review
- Article
- From Sea to Skin: Is There a Future for Natural Photoprotectants?Marine drugs · 2021Review
- Photoreceptor Diversification Accompanies the Evolution of Anthozoa.Molecular biology and evolution · 2021Article
- Protein kinase A controls yeast growth in visible light.BMC biology · 2020Article
- Regulatory Impact of the C-Terminal Tail on Charge Transfer Pathways inMolecules (Basel, Switzerland) · 2020Article
- Functional Characterization ofFrontiers in microbiology · 2020Article
- Neurogenetic basis for circadian regulation of metabolism by the hypothalamus.Genes & development · 2019Review
- Fluorescently-labelled CPD and 6-4PP photolyases: new tools for live-cell DNA damage quantification and laser-assisted repair.Nucleic acids research · 2019Article
- EFFECTOR OF TRANSCRIPTION factors are novel plant-specific regulators associated with genomic DNA methylation in Arabidopsis.The New phytologist · 2019Article
- HyphaTracker: An ImageJ toolbox for time-resolved analysis of spore germination in filamentous fungi.Scientific reports · 2018Article
- Article
- Molecular genetic response to varied wavelengths of light in Xiphophorus maculatus skin.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2015Article
- Kinetic studies on the oxidation of semiquinone and hydroquinone forms of Arabidopsis cryptochrome by molecular oxygen.FEBS open bio · 2015Article
- DNA damage and repair in plants - from models to crops.Frontiers in plant science · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blue light governs a number of cellular responses in bacteria, plants, and animals, including photoreactivation, plant development, and circadian photoentrainment. These activities are mediated by a family of highly conserved flavoproteins, the photolyase/cryptochrome family. Photolyase binds to UV photoproducts in DNA and repairs them in a process called photoreactivation in which blue light is used to initiate a cyclic electron transfer to break bonds and restore the integrity of DNA. Cryptochrome, which has a high degree of sequence identity to photolyase, works as the main circadian photoreceptor and as a component of the molecular clock in animals, including mammals, and regulates growth and development in plants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.