ArticleProceedings of the National Academy of Sciences of the United States of America2002
Modularity and reshuffling of Snail and Slug expression during vertebrate evolution.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Article
- Untangling Zebrafish Genetic Annotation: Addressing Complexities and Nomenclature Issues in Orthologous Evaluation of TCOF1 and NOLC1.Journal of molecular evolution · 2024Article
- Schwann Cell Development and Myelination.Cold Spring Harbor perspectives in biology · 2024Review
- Cadherins in early neural development.Cellular and molecular life sciences : CMLS · 2021Review
- Spatiotemporal cellular movement and fate decisions during first pharyngeal arch morphogenesis.Science advances · 2020Article
- A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus.Scientific reports · 2019Article
- From neural crest cells to melanocytes: cellular plasticity during development and beyond.Cellular and molecular life sciences : CMLS · 2019Review
- Magic roundabout is an endothelial-specific ohnolog of ROBO1 which neo-functionalized to an essential new role in angiogenesis.PloS one · 2019Article
- Specification and formation of the neural crest: Perspectives on lineage segregation.Genesis (New York, N.Y. : 2000) · 2019Review
- Identity and novelty in the avian syrinx.Proceedings of the National Academy of Sciences of the United States of America · 2018Review
- Divergent axial morphogenesis and earlyEvoDevo · 2018Article
- Melanoblast development coincides with the late emerging cells from the dorsal neural tube in turtle Trachemys scripta.Scientific reports · 2017Article
- Article
- Context-specific roles of EMT programmes in cancer cell dissemination.Nature cell biology · 2017Article
- Recent advances in understanding the roles of whole genome duplications in evolution.F1000Research · 2017Review
- The emerging roles of ribosome biogenesis in craniofacial development.Frontiers in physiology · 2014Review
- The hypoxia factor Hif-1α controls neural crest chemotaxis and epithelial to mesenchymal transition.The Journal of cell biology · 2013Article
- Induction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions.Developmental biology · 2012Review
- Slug expression during melanoma progression.The American journal of pathology · 2012Article
- Evolution of anterior Hox regulatory elements among chordates.BMC evolutionary biology · 2011Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gene duplication has been a major mechanism for increasing genomic complexity and variation during evolution. The evolutionary history of duplicated genes has been poorly studied along the vertebrate lineage. Here, we attempt to study that history by analyzing the expression of two members of the Snail family, Snail and Slug, in representatives of the major vertebrate groups. We find a surprising degree of variability in a subset of the expression sites for both genes in different species. Although some of the changes can be explained by neofunctionalization or subfunctionalization, others imply reciprocal changes in the expression of the two genes and the reappearance of expression in sites lost earlier in evolution. Because these changes do not fit easily into current models, we need to invoke additional mechanisms acting on enhancer elements to distribute expression domains and functions of duplicated genes unequally during evolution.
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