ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2002
Factors affecting health related quality of life of patients with inflammatory bowel disease.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
61 citing papers in PubMed, 4 syntheses or guidelines pooled it, 199 citations in OpenAlex.
- Prevalence of disability in inflammatory bowel disease: a systematic review and meta-analysis.Inflammatory bowel diseases · 2026Pooled it
- Prevalence and Impact of Post-traumatic Stress Disorder in Gastrointestinal Conditions: A Systematic Review.Digestive diseases and sciences · 2021Pooled it
- The economic and quality-of-life burden of Crohn's disease in Europe and the United States, 2000 to 2013: a systematic review.Digestive diseases and sciences · 2015Pooled it
- Systematic review: The role of race and socioeconomic factors on IBD healthcare delivery and effectiveness.Inflammatory bowel diseases · 2013Pooled it
- Impact of an intervention program on drug adherence in patients with ulcerative colitis: Randomized clinical trial.PloS one · 2023Trial
- Biomechanical characteristics of upper airway muscles and their association with obstructive sleep apnea risk in industrial workers.Sleep & breathing = Schlaf & Atmung · 2026Article
- Phenotype-specific determinants of health-related quality of life in Crohn's disease and ulcerative colitis: a multicenter cross-sectional study.BMC gastroenterology · 2026Article
- Exploring Maladaptive Eating Behaviors and Quality of Life in Those with Bowel Diseases.Nutrients · 2025Article
- Impact of Inflammatory Bowel Disease on Quality of Life and Work Productivity in Patients Under Treatment.Cureus · 2025Article
- Trends and Factors Related to Quality of Life in Patients with Inflammatory Bowel Disease.Gut and liver · 2025Article
- Impact of musculoskeletal joint complaints on quality of life in patients with inflammatory bowel disease: a cross-sectional study.BMJ open · 2024Article
- Investigating resilience in patients with IBD: preliminary insights for understanding disease-specific resilience skills.Frontiers in psychology · 2024Article
- Comparison of a second TNFi vs other biologic or targeted synthetic DMARD following an initial TNFi.Journal of managed care & specialty pharmacy · 2023Article
- The Effect of Adherence to Mediterranean Diet on Disease Activity in Patients with Inflammatory Bowel Disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Has the COVID-19 Pandemic Worsened Health-Related Quality of Life of Patients with Inflammatory Bowel Disease? A Longitudinal Disease Activity-Controlled Study.International journal of environmental research and public health · 2023Article
- Constructing a prediction model of inflammatory bowel disease recurrence based on factors affecting the quality of life.Frontiers in medicine · 2023Article
- Selected Personality Traits and Employment as the Predictors of the Intensity of Psychosocial Problems Experienced by Chronically Ill Patients.International journal of environmental research and public health · 2022Article
- Health-Related Quality of Life of Patients Treated with Biological Agents and New Small-Molecule Drugs for Moderate to Severe Crohn's Disease: A Systematic Review.Journal of clinical medicine · 2022Review
- The Function of Occupational Activity for Health as Perceived by Chronically Ill People.International journal of environmental research and public health · 2022Article
- Health-related quality of life among Chinese patients with Crohn's disease: a cross-sectional survey using the EQ-5D-5L.Health and quality of life outcomes · 2022Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledUsing a disease specific instrument to measure the health related quality of life (HRQOL) of patients with inflammatory bowel disease (IBD), it has been shown that their perceived HRQOL worsens during active disease. The precise factors involved in HRQOL changes reported by these patients are largely unknown. Our aim was to elucidate which socio-demographic and health status variables are related with HRQOL in IBD patients. To this end, 354 patients with IBD were interviewed. To quantify the impairment in the HRQOL, the 36-item version of the inflammatory bowel disease questionnaire (IBDQ) was administered to all patients. To explore the relation of each individual variable on the HRQOL an univariate analysis by using the Spearman correlation, the Mann-Whitney or the Kruskal-Wallis test was performed when necessary. Factors significant at the univariate analysis were assessed using multiple linear regression modeling with global IBDQ score as the dependent factor.
resultsDisease type did not predict IBDQ score in the univariate nor in the multivariate analysis. Consequently, statistical analysis was performed in the global group of 354 patients independently of the type of disease. Lower recurrence/year index, longer disease duration, higher level of education, symptom activity, male gender and non-necessity of hospitalization all predict a better HRQOL (p < 0.05). Factors which remained significant (p < 0.05) in the multiple regression modeling were gender, need of hospitalization, symptomatic activity, recurrence/year index and education level.
conclusionsSymptomatic activity and socio-demographic variables such as gender and education are the most important factors involved in the impairment of HRQOL in patients with IBD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.