ArticlePlant physiology2002
Both vegetative and reproductive actin isovariants complement the stunted root hair phenotype of the Arabidopsis act2-1 mutation.
Article in Plant physiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 102 citations in OpenAlex.
- Actin Isovariant ACT2-Mediated Cellular Auxin Homeostasis Regulates Lateral Root Organogenesis in Arabidopsis thaliana.Cytoskeleton (Hoboken, N.J.) · 2026Article
- Actin-depolymerizing factors 8 and 11 promote root hair elongation at high pH.Plant communications · 2024Article
- Single Amino Acid Exchange in ACTIN2 Confers Increased Tolerance to Oxidative Stress in ArabidopsisInternational journal of molecular sciences · 2021Article
- Actin Is Required for Cellular Development and Virulence ofmSystems · 2020Article
- ACTIN7 Is Required for Perinuclear Clustering of Chloroplasts during Arabidopsis Protoplast Culture.Plants (Basel, Switzerland) · 2020Article
- Exogenous Nitro-Oleic Acid Treatment Inhibits Primary Root Growth by Reducing the Mitosis in the Meristem inFrontiers in plant science · 2020Article
- Single-point ACT2 gene mutation in the Arabidopsis root hair mutant der1-3 affects overall actin organization, root growth and plant development.Annals of botany · 2018Article
- Actin Reorganization Triggers Rapid Cell Elongation in Roots.Plant physiology · 2018Article
- Microfilament Depolymerization Is a Pre-requisite for Stem Cell Formation DuringFrontiers in plant science · 2017Article
- Role of Reactive Oxygen Species during Cell Expansion in Leaves.Plant physiology · 2016Article
- Recent Advances in Understanding the Molecular Mechanisms Regulating the Root System Response to Phosphate Deficiency in Arabidopsis.Current genomics · 2016Article
- A Cotton Annexin Affects Fiber Elongation and Secondary Cell Wall Biosynthesis Associated with Ca2+ Influx, ROS Homeostasis, and Actin Filament Reorganization.Plant physiology · 2016Article
- Functional divergence of GhCFE5 homoeologs revealed in cotton fiber and Arabidopsis root cell development.Plant cell reports · 2016Article
- Arabidopsis plants deficient in constitutive class profilins reveal independent and quantitative genetic effects.BMC plant biology · 2015Article
- Root hairs.The arabidopsis book · 2014Article
- Dynamic proteomics emphasizes the importance of selective mRNA translation and protein turnover during Arabidopsis seed germination.Molecular & cellular proteomics : MCP · 2014Article
- Plant cell shape: modulators and measurements.Frontiers in plant science · 2013Review
- Arabidopsis actin-depolymerizing factor7 severs actin filaments and regulates actin cable turnover to promote normal pollen tube growth.The Plant cell · 2013Article
- Patterning and lifetime of plasma membrane-localized cellulose synthase is dependent on actin organization in Arabidopsis interphase cells.Plant physiology · 2013Article
- AtFH1 formin mutation affects actin filament and microtubule dynamics in Arabidopsis thaliana.Journal of experimental botany · 2013Article
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4 authors at 1 institution in 1 country.
Funding
Abstract
The ACT2 gene, encoding one of eight actin isovariants in Arabidopsis, is the most strongly expressed actin gene in vegetative tissues. A search was conducted for physical defects in act2-1 mutant plants to account for their reduced fitness compared with wild type in population studies. The act2-1 insertion fully disrupted expression of ACT2 RNA and significantly lowered the level of total actin protein in vegetative organs. The root hairs of the act2-1 mutants were 10% to 70% the length of wild-type root hairs, and they bulged severely at the base. The length of the mutant root hairs and degree of bulging at the base were affected by adjusting the osmolarity and gelling agent of the growth medium. The act2-1 mutant phenotypes were fully rescued by an ACT2 genomic transgene. When the act2-1 mutation was combined with another vegetative actin mutation, act7-1, the resulting double mutant exhibited extensive synergistic phenotypes ranging from developmental lethality to severe dwarfism. Transgenic overexpression of the ACT7 vegetative isovariant and ectopic expression of the ACT1 reproductive actin isovariant also rescued the root hair elongation defects of the act2-1 mutant. These results suggest normal ACT2 gene regulation is essential to proper root hair elongation and that even minor differences may cause root defects. However, differences in the actin protein isovariant are not significant to root hair elongation, in sharp contrast to recent reports on the functional nonequivalency of plant actin isovariants. Impairment of root hair functions such as nutrient mining, water uptake, and physical anchoring are the likely cause of the reduced fitness seen for act2-1 mutants in multigenerational studies.
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