Evidence map›Paper›PMID 12479589›Full record

ReviewMolecular and cellular biochemistry2002

Ex-FABP, extracellular fatty acid binding protein, is a stress lipocalin expressed during chicken embryo development.

Fiorella Descalzi Cancedda, Beatrice Dozin, Barbara Zerega, Silvia Cermelli, Chiara Gentili, Ranieri Cancedda

Abstract readReview
PubMed
In one paragraph

Review in Molecular and cellular biochemistry, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Skin mucus proteins of lumpsucker (Biochemistry and biophysics reports · 2017
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Mouse 24p3 protein has an effect on L929 cell viability.International journal of biological sciences · 2007
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fiorella Descalzi CanceddaIstituto Nazionale per la Ricerca sul Cancro, Centro Biotecnologie Avanzate, Genova, Italy. descalzi@cba.unige.it
Beatrice Dozin
Barbara Zerega
Silvia Cermelli
Chiara Gentili
Ranieri Cancedda
Tecnologie Avanzate (Italy) · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular Fatty Acid Binding Protein (Ex-FABP) is a 21 kDa lipocalin, expressed during chicken embryo development in hypertrophic cartilage, in muscle fibres and in blood granulocyte. The protein selectively binds with high affinity fatty acids, preferably long chain unsaturated fatty acids in chondrocyte and myoblast cultures Ex-FABP expression is increased by inflammatory-agents and repressed by anti-inflammatory-agents. In adult cartilage, Ex-FABP is expressed only in pathological conditions such as in dyschondroplastic and osteoarthritic chicken cartilage. We propose that lipocalin Ex-FABP represents a stress protein physiologically expressed in tissues where active remodelling is taking place during development and also present in tissues characterized by a stress response due to pathological conditions.

Indexed as

Avian ProteinsAnimalsAnti-Inflammatory AgentsCarrier ProteinsChick EmbryoFatty Acid-Binding ProteinsFatty AcidsGene Expression Regulation, DevelopmentalLipocalin 1LipocalinsAnti-Inflammatory AgentsAvian ProteinsCarrier ProteinsCh21 protein, chickenFatty Acid-Binding ProteinsFatty AcidsLipocalin 1Lipocalins

Identifiers

PMID12479589
OpenAlexW1580893396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.