ReviewBreast cancer research : BCR2002
Insulin-like growth factors and insulin-like growth factor binding proteins in mammary gland function.
Review in Breast cancer research : BCR, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Association between the IGFBP-3 rs2854744 polymorphism and cancer risk: a meta-analysis.BMC medical genomics · 2026Pooled it
- IGFBP3 polymorphisms and risk of cancer: a meta-analysis.Molecular biology reports · 2010Pooled it
- Serial Imaging of Tumour and microEnvironment (SITE) platform for live-cellbioRxiv : the preprint server for biology · 2025Article
- Effect of red clover isoflavones on hormone, immune, inflammatory, and plasma biochemistry in lactating dairy cows.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Insulin promotes growth in breast cancer cells through the type I IGF receptor in insulin receptor deficient cells.Experimental cell research · 2024Article
- Insulin-like growth factor binding protein 5 accelerate the senescence of periodontal ligament stem cells.Cell and tissue banking · 2023Article
- Association of polycystic ovary syndrome with mammographic density in Turkish women: a population-based case-control study.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Chemical Effects on Breast Development, Function, and Cancer Risk: Existing Knowledge and New Opportunities.Current environmental health reports · 2022Review
- IGF Binding Protein-5 Induces Cell Senescence.Frontiers in endocrinology · 2018Review
- Association ofBioMed research international · 2018Observational
- Material-induced Senescence (MIS): Fluidity Induces Senescent Type Cell Death of Lung Cancer Cells via Insulin-Like Growth Factor Binding Protein 5.Theranostics · 2017Article
- MicroRNA-206 is differentially expressed in Brca1-deficient mice and regulates epithelial and stromal cell compartments of the mouse mammary gland.Oncogenesis · 2016Article
- Insulin-Like Growth Factor-2 Is Induced Following 5-Aminolevulinic Acid-Mediated Photodynamic Therapy in SW620 Human Colon Cancer Cell Line.International journal of molecular sciences · 2015Article
- Responses of the mammary transcriptome of dairy cows to altered photoperiod during late gestation.Physiological genomics · 2015Article
- Lifestyle, nutrition and breast cancer: facts and presumptions for consideration.Ecancermedicalscience · 2015Review
- Targeting the insulin-like growth factor pathway in hepatocellular carcinoma.World journal of hepatology · 2014Review
- Pharmacological overview of galactogogues.Veterinary medicine international · 2014Review
- Targeting the insulin-like growth factor receptor: developing biomarkers from gene expression profiling.Critical reviews in oncogenesis · 2012Review
- Article
- Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts.Proteomics · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insulin-like growth factor (IGF)-mediated proliferation and survival are essential for normal development in the mammary gland during puberty and pregnancy. IGFs interact with IGF-binding proteins and regulate their function. The present review focuses on the role of IGFs and IGF-binding proteins in the mammary gland and describes how modulation of their actions occurs by association with hormones, other growth factors and the extracellular matrix. The review will also highlight the involvement of the IGF axis in breast cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.