ArticleNucleic acids research2002
The complete genomic sequence of Mycoplasma penetrans, an intracellular bacterial pathogen in humans.
Article in Nucleic acids research, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
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Who cites it
91 citing papers in PubMed, 218 citations in OpenAlex.
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- A sweeping view of avian mycoplasmas biology drawn from comparative genomic analyses.BMC genomics · 2025Article
- Screening the receptors forFrontiers in cellular and infection microbiology · 2025Article
- Peritonitis caused byCase reports in women's health · 2024Article
- Conversion of the CG specific M.MpeI DNA methyltransferase into an enzyme predominantly methylating CCA and CCC sites.Nucleic acids research · 2024Article
- Exploring gut microbiota in adult Atlantic salmon (Salmo salar L.): Associations with gut health and dietary prebiotics.Animal microbiome · 2023Article
- Characterization of Virulence-Associated Traits in Mycoplasma penetrans Strains Acting as Likely Etiological Agents of Idiopathic Nongonococcal Urethritis.The Journal of infectious diseases · 2023Article
- Complete Genomic Sequence of the Thermophilic Hydrogen-Oxidizing Methanogen Methanothermobacter tenebrarum Strain RMASMicrobiology resource announcements · 2022Article
- Cell shape controls rheotaxis in small parasitic bacteria.PLoS pathogens · 2022Article
- Thymidine utilisation pathway is a novel phenotypic switch ofJournal of medical microbiology · 2022Article
- The genome and antigen proteome analysis ofFrontiers in microbiology · 2022Article
- Genome erosion and evidence for an intracellular niche - exploring the biology of mycoplasmas in Atlantic salmon.Aquaculture (Amsterdam, Netherlands) · 2021Article
- Metal utilization in genome-reduced bacteria: Do human mycoplasmas rely on iron?Computational and structural biotechnology journal · 2021Review
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- Mycoplasma penetrans bacteremia in an immunocompromised patient detected by metagenomic sequencing: a case report.BMC infectious diseases · 2020Article
- Population Genetic Divergence and Environment Influence the Gut Microbiome in Oregon Threespine Stickleback.Genes · 2019Article
- Fecal Bacteriome and Mycobiome in Bats with Diverse Diets in South China.Current microbiology · 2018Article
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31 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The complete genomic sequence of an intracellular bacterial pathogen, Mycoplasma penetrans HF-2 strain, was determined. The HF-2 genome consists of a 1 358 633 bp single circular chromosome containing 1038 predicted coding sequences (CDSs), one set of rRNA genes and 30 tRNA genes. Among the 1038 CDSs, 264 predicted proteins are common to the Mycoplasmataceae sequenced thus far and 463 are M.penetrans specific. The genome contains the two-component system but lacks the essential cellular gene, uridine kinase. The relatively large genome of M.penetrans HF-2 among mycoplasma species may be accounted for by both its rich core proteome and the presence of a number of paralog families corresponding to 25.4% of all CDSs. The largest paralog family is the p35 family, which encodes surface lipoproteins including the major antigen, P35. A total of 44 genes for p35 and p35 homologs were identified and 30 of them form one large cluster in the chromosome. The genetic tree of p35 paralogs suggests the occurrence of dynamic chromosomal rearrangement in paralog formation during evolution. Thus, M.penetrans HF-2 may have acquired diverse repertoires of antigenic variation-related genes to allow its persistent infection in humans.
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