ArticleEukaryotic cell2002
Early acquisition of Pneumocystis carinii in neonatal rats as evidenced by PCR and oral swabs.
Article in Eukaryotic cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Detection ofJournal of fungi (Basel, Switzerland) · 2023Article
- Article
- Update on invasive fungal infections in the Middle Eastern and North African region.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Review
- A Molecular Window into the Biology and Epidemiology of Pneumocystis spp.Clinical microbiology reviews · 2018Review
- High transient colonization by Pneumocystis jirovecii between mothers and newborn.European journal of pediatrics · 2017Article
- The Prevalence of Pneumocystis jiroveci in Bronchoalveolar Lavage Specimens of Lung Transplant Recipients Examined by the Nested PCR.Jundishapur journal of microbiology · 2014Article
- Pneumocystis.Cold Spring Harbor perspectives in medicine · 2014Review
- Infections in the immunosuppressed host.Annals of the American Thoracic Society · 2014Review
- Detection of Pneumocystis in the nasal swabs of immune-suppressed rats by use of PCR and microscopy.Medical science monitor basic research · 2013Article
- Near-universal prevalence of Pneumocystis and associated increase in mucus in the lungs of infants with sudden unexpected death.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013Article
- Microbial antigenic variation mediated by homologous DNA recombination.FEMS microbiology reviews · 2012Review
- Chitinases in Pneumocystis carinii pneumonia.Medical microbiology and immunology · 2012Article
- Update on the diagnosis and treatment of Pneumocystis pneumonia.Therapeutic advances in respiratory disease · 2011Review
- Are members of the fungal genus pneumocystis (a) commensals; (b) opportunists; (c) pathogens; or (d) all of the above?PLoS pathogens · 2010Article
- Article
- Complexity of the MSG gene family of Pneumocystis carinii.BMC genomics · 2009Article
- Epidemiology of Pneumocystis colonization in families.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2008Article
- Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite.PloS one · 2007Article
- Primary pneumocystis infection in infants hospitalized with acute respiratory tract infection.Emerging infectious diseases · 2007Article
- Noninvasive method for monitoring Pneumocystis carinii pneumonia.Emerging infectious diseases · 2003Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The complete life cycle of Pneumocystis carinii has not been defined, but accumulating evidence suggests that the mammalian host may acquire this organism early in life. In the present study, the initial time of P. carinii acquisition was determined in rats by amplification of P. carinii DNA in oral swabs from seven sets of pups and dams and from fetal tissue obtained by cesarean section of three gravid female rats. DNA extracted from all samples was amplified by using PCR primers directed to the P. carinii mitochondrial large subunit rRNA. Amplicons were produced from 80% (28 of 35) of pups within 2 h after birth; from 97% (34 of 35) after 24 h, and in all of the serially sampled pups by 48 h. No P. carinii amplicons were produced from 48 fetuses or their placentae taken by cesarean section. Thus, P. carinii is acquired almost immediately after birth, and placental transmission occurs rarely, if ever, in rats.
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