Evidence map›Paper›PMID 12455968›Full record

ReviewEukaryotic cell2002

Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress.

Alan G Hinnebusch, Krishnamurthy Natarajan

Abstract readReview
In one paragraph

Review in Eukaryotic cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 175 papers.

0numbers the graph read from it
0cells of the map it votes in
175citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

175 citing papers in PubMed.

  1. An atlas of thebioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Gene regulatory networks in disease and ageing.Nature reviews. Nephrology · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Multiomics ofInternational journal of molecular sciences · 2023
    Article
  18. Article
  19. Article
  20. Review

115 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alan G HinnebuschLaboratory of Gene Regulation and Development, National Institute of Child Health and Human Development, Bethesda, Maryland 20892, USA. ahinnebusch@nih.gov
Krishnamurthy Natarajan

Funding

Translational & Transcriptional Control Of Gene Expression By Nutrients In YeastZIAHD001004 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI HINNEBUSCH, ALAN G · 2009 to 2025
$34.4M
Translational &Transcriptional Control Of GenesZ01HD001004 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI HINNEBUSCH, ALAN G · 1985 to 2008
$5.7M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression RegulationAnimalsDNA-Binding ProteinsEukaryotic CellsMammalsProtein BiosynthesisProtein KinasesProtein Serine-Threonine KinasesSaccharomyces cerevisiae ProteinsTranscription, GeneticDNA-Binding ProteinsGCN2 protein, S cerevisiaeProtein KinasesProtein Serine-Threonine KinasesSaccharomyces cerevisiae Proteins

Identifiers

PMID12455968
PMCPMC118051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.