ArticleEukaryotic cell2002
Distinct signaling pathways from the circadian clock participate in regulation of rhythmic conidiospore development in Neurospora crassa.
Article in Eukaryotic cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Methylxanthines Modulate Circadian Period Length Independently of the Action of Phosphodiesterase.Microbiology spectrum · 2023Article
- Exposure to Artificial Light at Night and the Consequences for Flora, Fauna, and Ecosystems.Frontiers in neuroscience · 2020Review
- A HAD family phosphatase CSP-6 regulates the circadian output pathway in Neurospora crassa.PLoS genetics · 2018Article
- The genetics of circadian rhythms in Neurospora.Advances in genetics · 2011Review
- Regulation by blue light of the fluffy gene encoding a major regulator of conidiation in Neurospora crassa.Genetics · 2010Article
- Neurospora crassa heat shock factor 1 Is an essential gene; a second heat shock factor-like gene, hsf2, is required for asexual spore formation.Eukaryotic cell · 2008Article
- Systems biology of the clock in Neurospora crassa.PloS one · 2008Article
- Conidiation rhythm and light entrainment in superoxide dismutase mutant in Neurospora crassa.Molecular genetics and genomics : MGG · 2008Article
- Fully codon-optimized luciferase uncovers novel temperature characteristics of the Neurospora clock.Eukaryotic cell · 2008Article
- Circadian rhythmicity mediated by temporal regulation of the activity of p38 MAPK.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- The band mutation in Neurospora crassa is a dominant allele of ras-1 implicating RAS signaling in circadian output.Genes & development · 2007Article
- Circadian output, input, and intracellular oscillators: insights into the circadian systems of single cells.Cold Spring Harbor symposia on quantitative biology · 2007Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Several different environmental signals can induce asexual spore development (conidiation) and expression of developmentally regulated genes in Neurospora crassa. However, under constant conditions, where no environmental cues for conidiation are present, the endogenous circadian clock in N. crassa promotes daily rhythms in expression of known developmental genes and of conidiation. We anticipated that the same pathway of gene regulation would be followed during clock-controlled conidiation and environmental induction of conidiation and that the circadian clock would need only to control the initial developmental switch. Previous experiments showed that high-level developmental induction of the clock-controlled genes eas (ccg-2) and ccg-1 requires the developmental regulatory proteins FL and ACON-2, respectively, and normal developmental induction of fl mRNA expression requires ACON-2. We demonstrate that the circadian clock regulates rhythmic fl gene expression and that fl rhythmicity requires ACON-2. However, we find that clock regulation of eas (ccg-2) is normal in an fl mutant strain and ccg-1 expression is rhythmic in an acon-2 mutant strain. Together, these data point to the endogenous clock and the environment following separate pathways to regulate conidiation-specific gene expression.
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