Evidence map›Paper›PMID 12454070›Full record

ArticleGenetics2002

The Y chromosome of Drosophila melanogaster exhibits chromosome-wide imprinting.

Keith A Maggert, Kent G Golic

Abstract read
In one paragraph

Article in Genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Quantification of variegatedBiology methods & protocols · 2025
    Article
  3. Article
  4. Live analysis of position-effect variegation inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  5. Monitoring of switches in heterochromatin-induced silencing shows incomplete establishment and developmental instabilities.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Endogenously imprinted genes in Drosophila melanogaster.Molecular genetics and genomics : MGG · 2014
    Article
  12. Article
  13. Site-specific genetic engineering of the Anopheles gambiae Y chromosome.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Keith A MaggertThe Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA. maggert@biology.utah.edu
Kent G Golic

Funding

PAIRING OF HOMOLOGOUS SEQUENCES IN DROSOPHILAR01GM060700 · NIGMS · UNIVERSITY OF UTAH · PI GOLIC, KENT G · 1999 to 2002
$522k
Genetic Dissection: Imprinting Drosophila melanogasterF32GM065777 · NIGMS · UNIVERSITY OF UTAH · PI MAGGERT, KEITH A · 2001 to 2003
$127k
NIGMS NIH HHS GM-60700NIGMS NIH HHS GM-65777-01
6 · The paper itself

Abstract

Genomic imprinting is well known as a regulatory property of a few specific chromosomal regions and leads to differential behavior of maternally and paternally inherited alleles. We surveyed the activity of two reporter genes in 23 independent P-element insertions on the heterochromatic Y chromosome of Drosophila melanogaster and found that all but one location showed differential expression of one or both genes according to the parental source of the chromosome. In contrast, genes inserted in autosomal heterochromatin generally did not show imprint-regulated expression. The imprints were established on Y-linked transgenes inserted into many different sequences and locations. We conclude that genomic imprinting affecting gene expression is a general property of the Drosophila Y chromosome and distinguishes the Y from the autosomal complement.

Indexed as

Genomic ImprintingAnimalsChromosome MappingCrosses, GeneticDNA Transposable ElementsDrosophila melanogasterFemaleHeterochromatinMaleTransgenesY ChromosomeDNA Transposable ElementsHeterochromatin

Identifiers

PMID12454070
PMCPMC1462351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.