Evidence map›Paper›PMID 12453343›Full record

ArticleEmerging infectious diseases2002

Molecular epidemiology of tuberculosis in a sentinel surveillance population.

Barbara A Ellis, Jack T Crawford, Christopher R Braden, Scott J N McNabb, Marisa Moore, Steve Kammerer, National Tuberculosis Genotyping and Surveillance Network Work Group

Registry-linked trialAbstract read
In one paragraph

Article in Emerging infectious diseases, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00173433 (The Importance of Exogenous Reinfection in the Tuberculosis Endemic of Taiwan), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00173433 completednot on this mapstarted 2005, after this paper: background citation

The Importance of Exogenous Reinfection in the Tuberculosis Endemic of Taiwan

TypeobservationalSponsorNational Taiwan University HospitalRan2005 to 2006Enrolled150ConditionsTuberculosis
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Observational
  4. Clustering and recent transmission ofInfection and drug resistance · 2018
    Article
  5. Article
  6. Article
  7. Article
  8. Risk factors for transmission of tuberculosis among United States-born African Americans and Whites.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2015
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  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Factors associated with genotype clustering of Mycobacterium tuberculosis isolates in an ethnically diverse region of southern California, United States.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2012
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Barbara A EllisCenters for Disease Control and Prevention, Atlanta, GA 30333, USA. bae7@cdc.gov
Jack T Crawford
Christopher R Braden
Scott J N McNabb
Marisa Moore
Steve Kammerer
National Tuberculosis Genotyping and Surveillance Network Work Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a population-based study to assess demographic and risk-factor correlates for the most frequently occurring Mycobacterium tuberculosis genotypes from tuberculosis (TB) patients. The study included all incident, culture-positive TB patients from seven sentinel surveillance sites in the United States from 1996 to 2000. M. tuberculosis isolates were genotyped by IS6110-based restriction fragment length polymorphism and spoligotyping. Genotyping was available for 90% of 11923 TB patients. Overall, 48% of cases had isolates that matched those from another patient, including 64% of U.S.-born and 35% of foreign-born patients. By logistic regression analysis, risk factors for clustering of genotypes were being male, U.S.-born, black, homeless, and infected with HIV; having pulmonary disease with cavitations on chest radiograph and a sputum smear with acid-fast bacilli; and excessive drug or alcohol use. Molecular characterization of TB isolates permitted risk correlates for clusters and specific genotypes to be described and provided information regarding cluster dynamics over time.

Indexed as

Sentinel SurveillanceAdolescentAdultAgedAntitubercular AgentsChildChild, PreschoolCluster AnalysisDNA, BacterialDrug Resistance, Multiple, BacterialFemaleGenotypeHumansInfantLongitudinal StudiesMaleAntitubercular AgentsDNA, Bacterial

Identifiers

PMID12453343
PMCPMC2738559

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.