Evidence map›Paper›PMID 12448776›Full record

ArticleJournal of anatomy2002

Ultrastructural analysis of pancreatic acinar cells from mice fed on genetically modified soybean.

Manuela Malatesta, Chiara Caporaloni, Luigia Rossi, Serafina Battistelli, Marco B L Rocchi, Francesco Tonucci, Giancarlo Gazzanelli

Abstract read
In one paragraph

Article in Journal of anatomy, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. RoundupToxics · 2019
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. How safe does transgenic food need to be?Nature biotechnology · 2013
    Article
  8. Scientific Opinion on applications (EFSA-GMO-RX-40-3-2EFSA journal. European Food Safety Authority · 2010
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manuela MalatestaIstituto di Istologia e Analisi di Laboratorio, University of Urbino, Italy. malatesta@uniurb.it
Chiara Caporaloni
Luigia Rossi
Serafina Battistelli
Marco B L Rocchi
Francesco Tonucci
Giancarlo Gazzanelli

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

No direct evidence that genetically modified (GM) food may represent a possible danger for health has been reported so far; however, the scientific literature in this field is quite poor. Therefore, we investigated the possible effects of a diet containing GM soybean on mouse exocrine pancreas by means of ultrastructural, morphometrical and immunocytochemical analyses. Our observations demonstrate that, although no structural modification occurs in pancreatic acinar cells of mice fed on GM soybean, quantitative changes of some cellular constituents take place in comparison to control animals. In particular, a diet containing significant amount of GM food seems to influence the zymogen synthesis and processing.

Indexed as

Food, Genetically ModifiedGlycine maxImage Processing, Computer-Assistedalpha-AmylasesAnimalsCell NucleusEndoplasmic Reticulum, RoughFemaleGolgi ApparatusMiceMice, Inbred StrainsMicroscopy, ElectronPancreasSecretory VesiclesSpectrophotometryalpha-Amylases

Identifiers

PMID12448776
PMCPMC1570979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.