ArticleJournal of bacteriology2002
Cross-regulation between a novel two-component signal transduction system for catabolism of toluene in Pseudomonas mendocina and the TodST system from Pseudomonas putida.
Article in Journal of bacteriology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Engineering NIR-sighted bacteria.eLife · 2025Article
- Discovery of an Inducible Toluene Monooxygenase That Cooxidizes 1,4-Dioxane and 1,1-Dichloroethylene in PropanotrophicApplied and environmental microbiology · 2020Article
- Microbial Metabolic Potential of Phenol Degradation in Wastewater Treatment Plant of Crude Oil Refinery: Analysis of Metagenomes and Characterization of Isolates.Microorganisms · 2020Article
- Nanomolar Responsiveness of an Anaerobic Degradation Specialist to Alkylphenol Pollutants.Journal of bacteriology · 2020Article
- Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.The Journal of biological chemistry · 2016Article
- Cloning of Toluene 4-Monooxygenase Genes and Application of Two-Phase System to the Production of the Anticancer Agent, Indirubin.Molecular biotechnology · 2015Article
- Multiple signals modulate the activity of the complex sensor kinase TodS.Microbial biotechnology · 2015Article
- Study of the TmoS/TmoT two-component system: towards the functional characterization of the family of TodS/TodT like systems.Microbial biotechnology · 2012Article
- FimR and FimS: biofilm formation and gene expression in Porphyromonas gingivalis.Journal of bacteriology · 2010Article
- The sensor kinase TodS operates by a multiple step phosphorelay mechanism involving two autokinase domains.The Journal of biological chemistry · 2009Article
- Outer-membrane transport of aromatic hydrocarbons as a first step in biodegradation.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Bacterial sensor kinase TodS interacts with agonistic and antagonistic signals.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- The TodS-TodT two-component regulatory system recognizes a wide range of effectors and works with DNA-bending proteins.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Expression microarray and mouse virulence analysis of four conserved two-component gene regulatory systems in group a streptococcus.Infection and immunity · 2006Article
- Transcriptional activation of quinoline degradation operons of Pseudomonas putida 86 by the AraC/XylS-type regulator OxoS and cross-regulation of the PqorM promoter by XylS.Applied and environmental microbiology · 2005Article
- Proteomic analysis reveals the participation of energy- and stress-related proteins in the response of Pseudomonas putida DOT-T1E to toluene.Journal of bacteriology · 2005Article
- Dual role of response regulator StyR in styrene catabolism regulation.Applied and environmental microbiology · 2005Article
- Bacterial transcriptional regulators for degradation pathways of aromatic compounds.Microbiology and molecular biology reviews : MMBR · 2004Review
- Characterization of transcriptional regulatory genes for biphenyl degradation in Rhodococcus sp. strain RHA1.Journal of bacteriology · 2004Article
- Genetic engineering of a highly solvent-tolerant Pseudomonas putida strain for biotransformation of toluene to p-hydroxybenzoate.Applied and environmental microbiology · 2003Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The tmoABCDEF genes encode the toluene-4-monooxygenase from Pseudomonas mendocina KR1. Upstream from the tmoA gene an open reading frame, tmoX, encoding a protein 83% identical to TodX (todX being the initial gene in the todXFC1C2BADEGIH operon from Pseudomonas putida DOT-T1E) was found. The tmoX gene is also the initial gene in the tmoXABCDEF gene cluster. The transcription initiation point from the tmoX promoter was mapped, and the sequence upstream revealed striking identity with the promoter of the tod operon of P. putida. The tod operon is regulated by a two-component signal transduction system encoded by the todST genes. Two novel genes from P. mendocina KR1, tmoST, were rescued by complementation of a P. putida DOT-T1E todST knockout mutant, whose gene products shared about 85% identity with TodS-TodT. We show that transcription from P(tmoX) and P(todX) can be mediated by TmoS-TmoT or TodS-TodT, in the presence of toluene, revealing cross-regulation between these two catabolic pathways.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.