ArticleThe Biochemical journal2003
Spatial characterisation of ryanodine-induced calcium release in mouse pancreatic acinar cells.
Article in The Biochemical journal, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Sexual Dimorphism in a Reciprocal Interaction of Ryanodine and IPThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Calcium signaling of pancreatic acinar cells in the pathogenesis of pancreatitis.World journal of gastroenterology · 2014Review
- Modelling mechanism of calcium oscillations in pancreatic acinar cells.Journal of bioenergetics and biomembranes · 2014Article
- Modelling the transition from simple to complex Ca²⁺ oscillations in pancreatic acinar cells.Journal of biosciences · 2014Article
- Caffeine and 2-Aminoethoxydiphenyl Borate (2-APB) Have Different Ability to Inhibit Intracellular Calcium Mobilization in Pancreatic Acinar Cell.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2010Article
- The ryanodine receptor mediates early zymogen activation in pancreatitis.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- Calcium release from presynaptic ryanodine-sensitive stores is required for long-term depression at hippocampal CA3-CA3 pyramidal neuron synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors.The Journal of cell biology · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In pancreatic acinar cells, agonists evoke intracellular Ca(2+) transients which are initiated in the apical region of these polarized cells. There are contradictory experimental data concerning Ca(2+) release from ryanodine receptors (RyRs) in the apical region. In the present study, we have used low doses of ryanodine to open RyRs leading to the release of Ca(2+) from intracellular stores. Ryanodine causes Ca(2+) release that is initiated in the apical region of the cell but is dependent upon functional inositol 1,4,5-trisphosphate receptors (IP(3)Rs). These results suggests that co-ordinated release from co-localized RyRs and IP(3)Rs underlies the increased sensitivity of the apical region to initiation of intracellular Ca(2+) transients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.