ArticleInfection and immunity2002
Rough lipopolysaccharide from Brucella abortus and Escherichia coli differentially activates the same mitogen-activated protein kinase signaling pathways for tumor necrosis factor alpha in RAW 264.7 macrophage-like cells.
Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- Brucellosis Complicated by Thyroid Abscess and Life-Threatening Hemophagocytic Syndrome: A Case Report.Infection and drug resistance · 2026Article
- Comparison of Biological and Immunological Characterization of Lipopolysaccharides From Brucella abortus RB51 and S19.Jundishapur journal of microbiology · 2015Article
- Ontology-based representation and analysis of host-Brucella interactions.Journal of biomedical semantics · 2015Article
- Transcriptome analysis of HeLa cells response to Brucella melitensis infection: a molecular approach to understand the role of the mucosal epithelium in the onset of the Brucella pathogenesis.Microbes and infection · 2012Article
- LPS-induced formation of immunoproteasomes: TNF-α and nitric oxide production are regulated by altered composition of proteasome-active sites.Cell biochemistry and biophysics · 2011Article
- The proteasome regulates bacterial CpG DNA-induced signaling pathways in murine macrophages.Shock (Augusta, Ga.) · 2010Article
- Interaction of Brucella suis and Brucella abortus rough strains with human dendritic cells.Infection and immunity · 2007Article
- Regulation of the mitogen-activated protein kinases by Brucella spp. expressing a smooth and rough phenotype: relationship to pathogen invasiveness.Infection and immunity · 2005Article
- Sphingosine kinase protects lipopolysaccharide-activated macrophages from apoptosis.Molecular and cellular biology · 2004Article
- Pathogenesis of malaria and clinically similar conditions.Clinical microbiology reviews · 2004Review
- Heme oxygenase-1 in cholecystokinin-octapeptipe attenuated injury of pulmonary artery smooth muscle cells induced by lipopolysaccharide and its signal transduction mechanism.World journal of gastroenterology · 2004Article
- Different responses of macrophages to smooth and rough Brucella spp.: relationship to virulence.Infection and immunity · 2004Article
- Brucella abortus rough mutants are cytopathic for macrophages in culture.Infection and immunity · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The intracellular, gram-negative pathogen Brucella abortus establishes chronic infections in host macrophages while downregulating cytokines such as tumor necrosis factor alpha (TNF-alpha). When producing TNF-alpha, Brucella abortus rough lipopolysaccharide (LPS) activates the same mitogen-activated protein kinase signaling pathways (ERK and JNK) as Escherichia coli LPS, but Brucella LPS is a much less potent agonist.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.