ReviewCurrent rheumatology reports2002
Gut inflammation and spondyloarthropathies.
Review in Current rheumatology reports, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 71 citations in OpenAlex.
- Internet-based randomised controlled trials for the evaluation of complementary and alternative medicines: probiotics in spondyloarthropathy.BMC musculoskeletal disorders · 2008Trial
- Gut expression of CD71 and co-localisation with Dec-1 associated with high levels of serum SIgA and disease activity in SpA.Scientific reports · 2025Article
- Elevated Calprotectin Levels Reveal Loss of Vascular Pattern and Atrophy of Villi in Ileum by Digital Chromoendoscopy and Magnification Colonoscopy in Patients with Spondyloarthritis Without Having Inflammatory Bowel Disease.Diagnostics (Basel, Switzerland) · 2024Article
- Study of vertebral fracture and Scanographic Bone Attenuation Coefficient in rheumatoid arthritis and ankylosing spondylitis vs. controls.Scientific reports · 2019Article
- The colon and terminal ileum in patients with ankylosing spondylitis and controls in Bangladesh: a macroscopic and microscopic study.Rheumatology advances in practice · 2018Article
- Capsule Endoscopy for Ileitis with Potential Involvement of Other Sections of the Small Bowel.Gastroenterology research and practice · 2016Review
- Update on ankylosing spondylitis: current concepts in pathogenesis.Current allergy and asthma reports · 2015Review
- Inflammatory bowel disease-related arthritis - clinical evaluation and possible role of cytokines.Reumatologia · 2015Article
- Osteoporosis: a paradox in ankylosing spondylitis.Current osteoporosis reports · 2011Article
- Article
- The colon in patients with ankylosing spondylitis and in normal controls in Bangladesh: a macroscopic and microscopic study.Clinical rheumatology · 2010Article
- [Enteropathic arthritis: water in the intestines, fire in the joints].Zeitschrift fur Rheumatologie · 2009Review
- Gastrointestinal lesions associated with spondyloarthropathies.World journal of gastroenterology · 2009Review
- The clinical significance of focal enhanced gastritis in adults with isolated ileitis of the terminal ileum.Journal of gastroenterology · 2008Article
- COX 2 inhibition and bowel strictures.Gut · 2004Article
- Experimental colitis does not increase the prevalence of ANKENT, a spontaneous joint disease in mice.Folia microbiologica · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spondyloarthropathies (SpA) are a group of related disorders with common clinical and genetic characteristics. The prototype disease in this group is ankylosing spondylitis; other entities include reactive arthritis, psoriatic arthritis, and arthritis in patients with inflammatory bowel disease. Over recent years, there has been a special interest in the relation between spondylitis/synovitis and gut inflammation in patients with SpA. Two thirds of patients with undifferentiated SpA show histologic signs of gut inflammation, and a fraction of these patients go on to develop clinically overt Crohn's disease. In this review, the authors will focus on 1) the growing evidence that has been provided that gut inflammation in SpA is immunologically related to Crohn's disease, based on the molecular characterization of the inflammation (lymphocyte homing markers and ligands, T cell cytokines, macrophage markers, and serology); and 2) on the therapeutic implications resulting from this concept. The recent introduction and positioning of anti-tumor necrosis factor-alpha therapy in patients with ankylosing spondylitis and other types of SpA is, in large part, based on this concept.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.