ArticleThe EMBO journal2002
MinCD-dependent regulation of the polarity of SpoIIIE assembly and DNA transfer.
Article in The EMBO journal, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Cell division machinery drives cell-specific gene activation during differentiation inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genetic Manipulation of Glycogen Allocation Affects Replicative Lifespan in E. coli.PLoS genetics · 2016Article
- Asymmetric division and differential gene expression during a bacterial developmental program requires DivIVA.PLoS genetics · 2014Article
- Complexity of bacterial phosphorylation interaction network.Frontiers in microbiology · 2014Article
- Open questions about the function and evolution of bacterial Min systems.Frontiers in microbiology · 2013Article
- An oscillating Min system in Bacillus subtilis influences asymmetrical septation during sporulation.Microbiology (Reading, England) · 2012Article
- Whole-genome sequencing and phenotypic analysis of Bacillus subtilis mutants following evolution under conditions of relaxed selection for sporulation.Applied and environmental microbiology · 2011Article
- Membrane-associated DNA transport machines.Cold Spring Harbor perspectives in biology · 2010Review
- Fully efficient chromosome dimer resolution in Escherichia coli cells lacking the integral membrane domain of FtsK.The EMBO journal · 2010Article
- Sequence-directed DNA export guides chromosome translocation during sporulation in Bacillus subtilis.Nature structural & molecular biology · 2008Article
- Bacterial growth and cell division: a mycobacterial perspective.Microbiology and molecular biology reviews : MMBR · 2008Review
- Cell-specific SpoIIIE assembly and DNA translocation polarity are dictated by chromosome orientation.Molecular microbiology · 2007Article
- Chromosome segregation in Bacillus subtilis.Folia microbiologica · 2007Review
- Requirement for the cell division protein DivIB in polar cell division and engulfment during sporulation in Bacillus subtilis.Journal of bacteriology · 2006Article
- Evidence that the SpoIIIE DNA translocase participates in membrane fusion during cytokinesis and engulfment.Molecular microbiology · 2006Article
- Chromosome segregation in Eubacteria.Current opinion in microbiology · 2003Review
- Bacterial cell division spirals into control.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Division site selection in Escherichia coli involves dynamic redistribution of Min proteins within coiled structures that extend between the two cell poles.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- The membrane domain of SpoIIIE is required for membrane fusion during Bacillus subtilis sporulation.Journal of bacteriology · 2003Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
During Bacillus subtilis sporulation, the SpoIIIE DNA translocase moves a trapped chromosome across the sporulation septum into the forespore. The direction of DNA translocation is controlled by the specific assembly of SpoIIIE in the mother cell and subsequent export of DNA into the forespore. We present evidence that the MinCD heterodimer, which spatially regulates cell division during vegetative growth, serves as a forespore-specific inhibitor of SpoIIIE assembly. The deletion of minCD increases the ability of forespore-expressed SpoIIIE to assemble and translocate DNA, and causes otherwise wild-type cells to reverse the direction of DNA transfer, producing anucleate forespores. We propose that two distinct mechanisms ensure the specific assembly of SpoIIIE in the mother cell, the partitioning of more SpoIIIE molecules into the larger mother cell by asymmetric cell division and the MinCD-dependent repression of SpoIIIE assembly in the forespore. Our results suggest that the ability of MinCD to sense positional information is utilized during sporulation to regulate protein assembly differentially on the two faces of the sporulation septum.
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Registered trials
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