ArticleThe EMBO journal2002
Cell numbers and leaf development in Arabidopsis: a functional analysis of the STRUWWELPETER gene.
Article in The EMBO journal, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 1 of them a synthesis that pooled it.
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Who cites it
101 citing papers in PubMed, 1 synthesis or guideline pooled it, 237 citations in OpenAlex.
- A multiscale growth atlas of Arabidopsis: linking cell dynamics to organ development.The New phytologist · 2026Pooled it
- Integrated Phylogenomics and Expression Profiling of the MED Gene Family inPlants (Basel, Switzerland) · 2026Article
- A simple and versatile plasma membrane staining method for visualizing living cell morphology in reproductive tissues across diverse plant species.Plant methods · 2025Article
- Identification of candidate genes for leaf size by QTL mapping and transcriptome sequencing in Brassica napus L.BMC genomics · 2025Article
- The trxG protein ULT1 regulates Arabidopsis organ size by interacting with TCP14/15 to antagonize the LIM peptidase DA1 for H3K4me3 on target genes.Plant communications · 2024Article
- Anisotropic cell growth at the leaf base promotes age-related changes in leaf shape in Arabidopsis thaliana.The Plant cell · 2023Article
- Multi-model genome-wide association studies of leaf anatomical traits and vein architecture in rice.Frontiers in plant science · 2023Article
- PHYTOCHROME-INTERACTING FACTOR 4/HEMERA-mediated thermosensory growth requires the Mediator subunit MED14.Plant physiology · 2022Article
- Environment-mediated mutagenetic interference on genetic stabilization and circadian rhythm in plants.Cellular and molecular life sciences : CMLS · 2022Review
- Leaf-size control beyond transcription factors: Compensatory mechanisms.Frontiers in plant science · 2022Review
- Functional Analysis ofFrontiers in plant science · 2021Article
- Cellular perspectives for improving mesophyll conductance.The Plant journal : for cell and molecular biology · 2020Review
- ORESARA15 Acts Synergistically with ANGUSTIFOLIA3 and Separately from AINTEGUMENTA to Promote Cell Proliferation during Leaf Growth.International journal of molecular sciences · 2019Article
- Transcriptional Repression of the APC/C Activator GenesThe Plant cell · 2019Article
- The plant Mediator complex and its role in jasmonate signaling.Journal of experimental botany · 2019Review
- Interaction map of Arabidopsis Mediator complex expounding its topology.Nucleic acids research · 2019Article
- The CIN-TCP transcription factors promote commitment to differentiation in Arabidopsis leaf pavement cells via both auxin-dependent and independent pathways.PLoS genetics · 2019Article
- Molecular and Phylogenetic Analyses of the Mediator Subunit Genes inFrontiers in genetics · 2019Article
- Are compound leaves more complex than simple ones? A multi-scale analysis.Annals of botany · 2018Article
- A role for MED14 and UVH6 in heterochromatin transcription upon destabilization of silencing.Life science alliance · 2018Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The struwwelpeter (swp) mutant in Arabidopsis shows reduced cell numbers in all aerial organs. In certain cases, this defect is partially compensated by an increase in final cell size. Although the mutation does not affect cell cycle duration in the young primordia, it does influence the window of cell proliferation, as cell number is reduced during the very early stages of primordium initiation and a precocious arrest of cell proliferation occurs. In addition, the mutation also perturbs the shoot apical meristem (SAM), which becomes gradually disorganized. SWP encodes a protein with similarities to subunits of the Mediator complex, required for RNA polymerase II recruitment at target promoters in response to specific activators. To gain further insight into its function, we overexpressed the gene under the control of a constitutive promoter. This interfered again with the moment of cell cycle arrest in the young leaf. Our results suggest that the levels of SWP, besides their role in pattern formation at the meristem, play an important role in defining the duration of cell proliferation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.