ArticleProceedings of the National Academy of Sciences of the United States of America2002
A chloroplast FKBP interacts with and affects the accumulation of Rieske subunit of cytochrome bf complex.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 109 citations in OpenAlex.
- Photosynthesis regulation, cell membrane stabilization and methylglyoxal detoxification seems major altered pathways under cold stress as revealed by integrated multi-omics meta-analysis.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Article
- Conserved Residues in the C-Terminal Domain Affect the Structure and Function of CYP38 in Arabidopsis.Frontiers in plant science · 2021Article
- A Rice Immunophilin Homolog, OsFKBP12, Is a Negative Regulator of Both Biotic and Abiotic Stress Responses.International journal of molecular sciences · 2020Article
- Fine mapping of the QTL cqSPDA2 for chlorophyll content in Brassica napus L.BMC plant biology · 2020Article
- Plant Cyclophilins: Multifaceted Proteins With Versatile Roles.Frontiers in plant science · 2020Review
- Chloroplast proteome response to drought stress and recovery in tomato (Solanum lycopersicum L.).BMC plant biology · 2017Article
- Maturation of PlastidFrontiers in plant science · 2017Review
- Chloroplast immunophilins.Protoplasma · 2016Review
- AtFKBP16-1, a chloroplast lumenal immunophilin, mediates response to photosynthetic stress by regulating PsaL stability.Physiologia plantarum · 2014Article
- Understanding the roles of the thylakoid lumen in photosynthesis regulation.Frontiers in plant science · 2013Review
- C-terminal processing of reaction center protein D1 is essential for the function and assembly of photosystem II in Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- The GreenCut: re-evaluation of physiological role of previously studied proteins and potential novel protein functions.Photosynthesis research · 2013Review
- A chloroplast membrane protein LTO1/AtVKOR involving in redox regulation and ROS homeostasis.Plant cell reports · 2013Article
- A Rice Immunophilin Gene, OsFKBP16-3, Confers Tolerance to Environmental Stress in Arabidopsis and Rice.International journal of molecular sciences · 2013Article
- Genome wide analysis of Cyclophilin gene family from rice and Arabidopsis and its comparison with yeast.Plant signaling & behavior · 2012Article
- The rice thylakoid lumenal cyclophilin OsCYP20-2 confers enhanced environmental stress tolerance in tobacco and Arabidopsis.Plant cell reports · 2012Article
- Lumen Thiol Oxidoreductase1, a disulfide bond-forming catalyst, is required for the assembly of photosystem II in Arabidopsis.The Plant cell · 2011Article
- Low abundance does not mean less importance in cysteine metabolism.Plant signaling & behavior · 2010Article
- Genome-wide analysis of genes encoding FK506-binding proteins in rice.Plant molecular biology · 2010Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunophilins are intracellular receptors of the immunosuppressants cyclosporin A, FK506, and rapamycin. Although all immunophilins possess peptidyl-prolyl isomerase activity and are identified from a wide range of organisms, little is known about their cellular functions. We report the characterization and functional analysis of an FK506 and rapamycin-binding protein (AtFKBP13) from Arabidopsis. The AtFKBP13 protein is synthesized as a precursor that is imported into chloroplasts and processed to the mature form located in the thylakoid lumen, as shown by chloroplast import assays and Western blot analysis. Experiments show that AtFKBP13 is translocated across the thylakoid membrane by the DeltapH-dependent pathway. Yeast two-hybrid screening identified Rieske FeS protein, a subunit of the cytochrome bf complex in the photosynthetic electron transport chain, as an interacting partner for AtFKBP13. Both yeast two-hybrid and in vitro protein-protein interaction assays showed that the precursor, but not the mature form, of AtFKBP13 interacted with Rieske protein, suggesting that interaction between the two proteins occurs along the import pathway. When AtFKBP13 expression was suppressed by RNA interference method, the level of Rieske protein was significantly increased in the transgenic plants.
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