ArticleThe Plant cell2002
Plant Rac-like GTPases are activated by auxin and mediate auxin-responsive gene expression.
Article in The Plant cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 203 citations in OpenAlex.
- The RALF-FERONIA Signaling Axis: A Central Hub Integrating Plant Growth, Reproduction, and Stress Responses.International journal of molecular sciences · 2025Review
- RLCKs phosphorylate RopGEFs to control auxin-dependent Arabidopsis development.Nature plants · 2025Article
- RALF-FER, a master ligand‒receptor pair in plant health.Crop health · 2025Review
- The cellular and molecular basis of the spur development inHorticulture research · 2024Article
- Stromal Ascorbate Peroxidase (Antioxidants (Basel, Switzerland) · 2023Article
- The RAC/ROP GTPase activator OsRopGEF10 functions in crown root development by regulating cytokinin signaling in rice.The Plant cell · 2023Article
- Article
- Molecular Mechanisms of Diverse Auxin Responses during Plant Growth and Development.International journal of molecular sciences · 2022Review
- FERONIA Receptor Kinase Integrates with Hormone Signaling to Regulate Plant Growth, Development, and Responses to Environmental Stimuli.International journal of molecular sciences · 2022Review
- A rich and bountiful harvest: Key discoveries in plant cell biology.The Plant cell · 2022Review
- Review
- Genome-wide, evolutionary, and functional analyses of ascorbate peroxidase (APX) family in Poaceae species.Genetics and molecular biology · 2022Article
- Developing specific leaf promoters tools for genetic use in transgenic plants towards food security.Saudi journal of biological sciences · 2021Article
- No Time for Transcription-Rapid Auxin Responses in Plants.Cold Spring Harbor perspectives in biology · 2021Review
- Function of membrane domains in rho-of-plant signaling.Plant physiology · 2021Review
- Genome-wide association study of inflorescence length of cultivated soybean based on the high-throughout single-nucleotide markers.Molecular genetics and genomics : MGG · 2019Article
- Barley susceptibility factor RACB modulates transcript levels of signalling protein genes in compatible interaction with Blumeria graminis f.sp. hordei.Molecular plant pathology · 2018Article
- In vivo monitoring of plant small GTPase activation using a Förster resonance energy transfer biosensor.Plant methods · 2018Article
- ROP GTPases Structure-Function and Signaling Pathways.Plant physiology · 2018Review
- Auxin Signaling.Plant physiology · 2018Review
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The auxin indole-3-acetic acid is a key plant hormone essential for a broad range of growth and developmental processes. Here, we show that auxin activates Rac-like GTPases (referred to as Rac/Rop GTPases), and they in turn stimulate auxin-responsive gene expression. In particular, we show that overexpressing a wild-type tobacco Rac/Rop GTPase, NtRac1, and its constitutively active mutant form activates auxin-responsive gene expression. On the other hand, overexpressing dominant-negative NtRac1 and Rac-negative regulators, or reducing the endogenous NtRac1 level, suppresses auxin-induced gene expression. Furthermore, overexpression of NtRac1 activity or suppression of its expression in transgenic seedlings induces phenotypes that are similar to auxin-related defects. Together, our results show that a subset of plant Rac/Rop GTPases functions in mediating the auxin signal to downstream responsive genes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.