Evidence map›Paper›PMID 12411509›Full record

ArticleThe EMBO journal2002

Rpb4 and Rpb9 mediate subpathways of transcription-coupled DNA repair in Saccharomyces cerevisiae.

Shisheng Li, Michael J Smerdon

Open access · bronzeAbstract read
In one paragraph

Article in The EMBO journal, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 132 citations in OpenAlex.

  1. Review
  2. Article
  3. Humanization of theGenes · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. DNA Repair in Haploid Context.International journal of molecular sciences · 2021
    Review
  13. Review
  14. The ELOF(1)ant in the room of TCR.Nature cell biology · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. A panorama of transcription-coupled repair in yeast chromatin.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shisheng LiBiochemistry and Biophysics, School of Molecular Biosciences, Washington State University, Pullman 99164-4660, USA.
Michael J Smerdon
Washington State University · US

Funding

DNA REPAIR IN A HORMONE-RESPONSIVE GENER01ES004106 · NIEHS · WASHINGTON STATE UNIVERSITY · PI SMERDON, MICHAEL J · 1986 to 2014
$4.5M
NIEHS NIH HHS ES04106NIEHS NIH HHS R01 ES004106
6 · The paper itself

Abstract

Rpb9, a non-essential subunit of RNA polymerase II, mediates a transcription-coupled repair (TCR) subpathway in Saccharomyces cerevisiae. This subpathway initiates at the same upstream site as the previously identified Rad26 subpathway. However, the Rpb9 subpathway operates more effectively in the coding region than in the region upstream of the transcription start site, whereas the Rad26 subpathway operates equally in the two regions. Rpb4, another non-essential subunit of RNA polymerase II, plays a dual role in regulating the two subpathways, suppressing the Rpb9 subpathway and facilitating the Rad26 subpathway. Simultaneous deletion of RPB9 and RAD26 genes completely abolishes TCR in both the coding and upstream regions, indicating that no other TCR subpathway exists in RNA polymerase II-transcribed genes.

Indexed as

Schizosaccharomyces pombe ProteinsBlotting, NorthernDNA, FungalDNA RepairRNA Polymerase IISaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription, GeneticDNA, FungalRNA Polymerase IIRPB4 protein, S cerevisiaeRpb9 protein, S pombeSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe Proteins

Identifiers

PMID12411509
PMCPMC131086
OpenAlexW2046195682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.