ArticleThe EMBO journal2002
Plo1(+) regulates gene transcription at the M-G(1) interval during the fission yeast mitotic cell cycle.
Article in The EMBO journal, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
- A new transcription factor for mitosis: in Schizosaccharomyces pombe, the RFX transcription factor Sak1 works with forkhead factors to regulate mitotic expression.Nucleic acids research · 2015Article
- Regulation of Ace2-dependent genes requires components of the PBF complex in Schizosaccharomyces pombe.Cell cycle (Georgetown, Tex.) · 2015Article
- Histone H2B ubiquitination promotes the function of the anaphase-promoting complex/cyclosome in Schizosaccharomyces pombe.G3 (Bethesda, Md.) · 2014Article
- Article
- Cyclin-dependent kinase 8 regulates mitotic commitment in fission yeast.Molecular and cellular biology · 2012Article
- Hpz1 modulates the G1-S transition in fission yeast.PloS one · 2012Article
- The RFX protein RfxA is an essential regulator of growth and morphogenesis in Penicillium marneffei.Eukaryotic cell · 2010Article
- Fission yeast Pcp1 links polo kinase-mediated mitotic entry to gamma-tubulin-dependent spindle formation.The EMBO journal · 2010Article
- Copy number suppressors of the Aspergillus nidulans nimA1 mitotic kinase display distinctive and highly dynamic cell cycle-regulated locations.Eukaryotic cell · 2008Article
- Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression.Nature cell biology · 2008Article
- Combined analysis reveals a core set of cycling genes.Genome biology · 2007Article
- Polo kinase controls cell-cycle-dependent transcription by targeting a coactivator protein.Nature · 2006Article
- Regulation of gene expression and cell division by Polo-like kinases.Current genetics · 2006Review
- The more the merrier: comparative analysis of microarray studies on cell cycle-regulated genes in fission yeast.Yeast (Chichester, England) · 2006Article
- The cell cycle-regulated genes of Schizosaccharomyces pombe.PLoS biology · 2005Article
- Identification of cell cycle-regulated genes in fission yeast.Molecular biology of the cell · 2005Article
- The forkhead transcription factor Fkh2 regulates the cell division cycle of Schizosaccharomyces pombe.Eukaryotic cell · 2004Article
- Global gene expression responses of fission yeast to ionizing radiation.Molecular biology of the cell · 2004Article
- Article
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9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The regulation of gene expression plays an important part in cell cycle controls. We describe the molecular machinery that co-ordinates gene transcription at the M-G(1) interval during the fission yeast mitotic cell cycle. A sequence is identified in the cdc15(+) promoter that we call a PCB (pombe cell cycle box), which confers M-G(1)-specific transcription. Sequences similar to the PCB are present in the promoters of seven other genes, spo12(+), cdc19(+), fin1(+), sid2(+), ppb1(+), mid1(+)/dmf1(+) and plo1(+), which we find to be transcribed at M-G(1). A transcription factor complex is identified that binds to the PCB sequence, which we name PBF, for PCB-binding factor. Finally, we show that PBF binding activity and consequent gene transcription are regulated by the Plo1p protein kinase, thus invoking a potential auto-feedback loop mechanism that regulates mitotic gene transcription and passage through septation and cytokinesis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.