ArticleNeoplasia (New York, N.Y.)
MRI of mouse models for gliomas shows similarities to humans and can be used to identify mice for preclinical trials.
Article in Neoplasia (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 73 citations in OpenAlex.
- OBSERVE: guidelines for the refinement of rodent cancer models.Nature protocols · 2024Review
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- Characterization of orthotopic xenograft tumor of glioma stem cells (GSCs) on MRI, PET and immunohistochemical staining.Frontiers in oncology · 2022Article
- Molecular imaging of a fluorescent antibody against epidermal growth factor receptor detects high-grade glioma.Scientific reports · 2021Article
- LPA signaling is regulated through the primary cilium: a novel target in glioblastoma.Oncogene · 2018Article
- Article
- Article
- Corticosteroids compromise survival in glioblastoma.Brain : a journal of neurology · 2016Article
- Evaluation of Concurrent Radiation, Temozolomide and ABT-888 Treatment Followed by Maintenance Therapy with Temozolomide and ABT-888 in a Genetically Engineered Glioblastoma Mouse Model.Neoplasia (New York, N.Y.) · 2016Article
- In vivo Mn-enhanced MRI for early tumor detection and growth rate analysis in a mouse medulloblastoma model.Neoplasia (New York, N.Y.) · 2014Article
- Aptamer-modified magnetic nanoprobe for molecular MR imaging of VEGFR2 on angiogenic vasculature.Nanoscale research letters · 2013Article
- Integrin αvβ3-targeted IRDye 800CW near-infrared imaging of glioblastoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2012Article
- Article
- MR imaging features of high-grade gliomas in murine models: how they compare with human disease, reflect tumor biology, and play a role in preclinical trials.AJNR. American journal of neuroradiology · 2012Review
- Characterization of a human tumorsphere glioma orthotopic model using magnetic resonance imaging.Journal of neuro-oncology · 2011Article
- Multiple-mouse MRI with multiple arrays of receive coils.Magnetic resonance in medicine · 2010Article
- Modeling Adult Gliomas Using RCAS/t-va Technology.Translational oncology · 2009Article
- VEGF immunopositivity related to malignancy degree, proliferative activity and angiogenesis in ENU-induced gliomas.Journal of molecular neuroscience : MN · 2007Article
- Imaging in neurooncology.NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2005Review
- mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma.Neoplasia (New York, N.Y.) · 2005Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Magnetic resonance imaging (MRI) has been utilized for screening and detecting brain tumors in mice based upon their imaging characteristics appearance and their pattern of enhancement. Imaging of these tumors reveals many similarities to those observed in humans with identical pathology. Specifically, high-grade murine gliomas have histologic characteristics of glioblastoma multiforme (GBM) with contrast enhancement after intravenous administration of gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA), implying disruption of the blood-brain barrier in these tumors. In contrast, low-grade murine oligodendrogliomas do not reveal contrast enhancement, similar to human tumors. MRI can be used to identify mice with brain neoplasms as inclusion criteria in preclinical trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.