ReviewBritish journal of cancer2002
Role of genetic polymorphisms in tumour angiogenesis.
Review in British journal of cancer, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Vascular endothelial growth factor gene polymorphisms and the risk of renal cell carcinoma: Evidence from eight case-control studies.Oncotarget · 2017Pooled it
- HIF-1α -1790G>A polymorphism significantly increases the risk of digestive tract cancer: a meta-analysis.World journal of gastroenterology · 2015Pooled it
- The GSTM1 null genotype increased risk of gastric cancer: a meta-analysis based on 46 studies.PloS one · 2013Pooled it
- Polymorphisms and clinical outcome in recurrent ovarian cancer treated with cyclophosphamide and bevacizumab.Clinical cancer research : an official journal of the American Association for Cancer Research · 2008Trial
- Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2008Trial
- The Relation of VEGFA, VEGFR2, VEGI, and HIF1A Genetic Variants and Their Serum Protein Levels with Breast Cancer in Egyptian Patients.Biochemical genetics · 2024Article
- Identification of Angiogenic Cargo in Extracellular Vesicles Secreted from Human Adipose Tissue-Derived Stem Cells and Induction of Angiogenesis In Vitro and In Vivo.Pharmaceutics · 2021Article
- Fibroblast growth factor receptor 4 single nucleotide polymorphism Gly388Arg in head and neck carcinomas.World journal of clinical oncology · 2019Article
- Correlations of MMP-2 and MMP-9 gene polymorphisms with the risk of hepatopulmonary syndrome in cirrhotic patients: A case-control study.The Kaohsiung journal of medical sciences · 2018Article
- Role ofOncotarget · 2017Article
- Association of the rs2071559 (T/C) polymorphism with lymphatic metastasis in patients with nasopharyngeal carcinoma.Oncology letters · 2017Article
- Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/STAT3 protein pathway.The Journal of biological chemistry · 2013Article
- Association of the VEGF 936C>T polymorphism with FDG uptake, clinical, histopathological, and metabolic response in patients with adenocarcinomas of the esophagogastric junction.Molecular imaging and biology · 2011Article
- Effect of vascular endothelial growth factor polymorphisms on survival in advanced-stage non-small-cell lung cancer.Cancer science · 2009Article
- Vascular endothelial growth factor polymorphisms and esophageal cancer prognosis.Clinical cancer research : an official journal of the American Association for Cancer Research · 2009Article
- Polymorphisms in the FGF2 gene and risk of serous ovarian cancer: results from the ovarian cancer association consortium.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2009Article
- Vascular endothelial growth factor-A specifies formation of native collaterals and regulates collateral growth in ischemia.Circulation research · 2008Article
- Clinical significance of a novel single nucleotide polymorphism in the 5' untranslated region of the Rabphillin-3A-Like gene in colorectal adenocarcinoma.Frontiers in bioscience : a journal and virtual library · 2008Article
- Genetic susceptibility to retinopathy of prematurity: the evidence from clinical and experimental animal studies.The British journal of ophthalmology · 2007Review
- FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients.British journal of cancer · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Angiogenesis plays a crucial role in the development, growth and spread of solid tumours. Pro- and anti-angiogenic factors are abnormally expressed in tumours, influencing tumour angiogenesis, growth and progression. Polymorphisms in genes encoding angiogenic factors or their receptors may alter protein expression and/or activity. This article reviews the literature to determine the possible role of angiogenesis-related polymorphisms in cancer. Further research studies in this potentially crucial area of tumour biology are proposed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.