Trial reportBMJ (Clinical research ed.)2002
Managing depression as a chronic disease: a randomised trial of ongoing treatment in primary care.
Trial report in BMJ (Clinical research ed.), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Nurse-led task-shifting strategies to substitute for mental health specialists in primary care: A systematic review.International journal of nursing practice · 2022Pooled it
- Rapid evidence review of the comparative effectiveness, harms, and cost-effectiveness of pharmacogenomics-guided antidepressant treatment versus usual care for major depressive disorder.Psychopharmacology · 2017Pooled it
- Cost-effectiveness of collaborative care for the treatment of depressive disorders in primary care: a systematic review.PloS one · 2015Pooled it
- Pooled it
- Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012Pooled it
- On-site mental health workers delivering psychological therapy and psychosocial interventions to patients in primary care: effects on the professional practice of primary care providers.The Cochrane database of systematic reviews · 2009Pooled it
- Depression in adults: psychological treatments and care pathways.BMJ clinical evidence · 2007Pooled it
- A systematic review of complex system interventions designed to increase recovery from depression in primary care.BMC health services research · 2006Pooled it
- Is remission of depressive symptoms in primary care a realistic goal? A meta-analysis.BMC family practice · 2004Pooled it
- Computerized adaptive measurement of depression: a simulation study.BMC psychiatry · 2004Pooled it
- Trial
- Detecting the effects of physician training in self-care interviewing skills: Coding of standardized patient (SP) visit recordings versus SP post-visit ratings.Patient education and counseling · 2017Trial
- Training Primary Care Physicians to Employ Self-Efficacy-Enhancing Interviewing Techniques: Randomized Controlled Trial of a Standardized Patient Intervention.Journal of general internal medicine · 2016Trial
- Chronic care management for substance dependence in primary care among patients with co-occurring disorders.Psychiatric services (Washington, D.C.) · 2015Trial
- Intervention impact on depression product appraisal and purchasing behavior by employers: a randomized trial.BMC health services research · 2014Trial
- Incremental benefits and cost of coordinated anxiety learning and management for anxiety treatment in primary care.Psychological medicine · 2012Trial
- Stakeholder benefit from depression disease management: differences by rurality?The journal of behavioral health services & research · 2011Trial
- Evaluation of a system of structured, pro-active care for chronic depression in primary care: a randomised controlled trial.BMC psychiatry · 2010Trial
- Collaborative care for depressed patients with chronic medical conditions: a randomized trial in Puerto Rico.Psychiatric services (Washington, D.C.) · 2010Trial
- Reducing suicidal ideation and depression in older primary care patients: 24-month outcomes of the PROSPECT study.The American journal of psychiatry · 2009Trial
3 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
Authors and funding
5 authors.
Funding
Abstract
objectivesTo evaluate the long term effect of ongoing intervention to improve treatment of depression in primary care.
designRandomised controlled trial.
settingTwelve primary care practices across the United States.
participants211 adults beginning a new treatment episode for major depression; 94% of patients assigned to ongoing intervention participated.
interventionPractices assigned to ongoing intervention encouraged participating patients to engage in active treatment, using practice nurses to provide care management over 24 months.
main outcome measuresPatients' report of remission and functioning.
resultsOngoing intervention significantly improved both symptoms and functioning at 24 months, increasing remission by 33 percentage points (95% confidence interval 7% to 46%), improving emotional functioning by 24 points (11 to 38) and physical functioning by 17 points (6 to 28). By 24 months, 74% of patients in enhanced care reported remission, with emotional functioning exceeding 90% of population norms and physical functioning approaching 75% of population norms.
conclusionsOngoing intervention increased remission rates and improved indicators of emotional and physical functioning. Studies are needed to compare the cost effectiveness of ongoing depression management with other chronic disease treatment routinely undertaken by primary care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.