ArticleProceedings of the National Academy of Sciences of the United States of America2002
A Lotus basic leucine zipper protein with a RING-finger motif negatively regulates the developmental program of nodulation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- Chemical screening in Fabaceae identified GPM1 as a novel compound enhancing early graft adhesion.Horticulture research · 2026Article
- Ubiquitination as a multi-layer regulatory network in legume-rhizobium symbiosis.Plant cell reports · 2026Review
- Identification of Novel Candidate Genes Associated With the Symbiotic Compatibility of Soybean With Rhizobia Under Natural Conditions.Plant direct · 2025Article
- Roles of a CCR4-NOT complex component GmNOT4-1 in regulating soybean nodulation.Frontiers in plant science · 2023Article
- Comprehensive Analysis ofGenes · 2022Article
- Pivotal roles of ELONGATED HYPOCOTYL5 in regulation of plant development and fruit metabolism in tomato.Plant physiology · 2022Article
- Involvement of Arachis hypogaea Jasmonate ZIM domain/TIFY proteins in root nodule symbiosis.Journal of plant research · 2021Article
- Genome-wide identification and evolutionary analysis of TGA transcription factors in soybean.Scientific reports · 2019Article
- Article
- OsbZIP48, a HY5 Transcription Factor Ortholog, Exerts Pleiotropic Effects in Light-Regulated Development.Plant physiology · 2018Article
- Identification of putative TAL effector targets of the citrus canker pathogens shows functional convergence underlying disease development and defense response.BMC genomics · 2014Article
- The identification of novel loci required for appropriate nodule development in Medicago truncatula.BMC plant biology · 2013Article
- Proteomic insights into intra- and intercellular plant-bacteria symbiotic association during root nodule formation.Frontiers in plant science · 2013Article
- Rapid phosphoproteomic and transcriptomic changes in the rhizobia-legume symbiosis.Molecular & cellular proteomics : MCP · 2012Article
- A Medicago truncatula tobacco retrotransposon insertion mutant collection with defects in nodule development and symbiotic nitrogen fixation.Plant physiology · 2012Article
- Rj (rj) genes involved in nitrogen-fixing root nodule formation in soybean.Breeding science · 2012Article
- Molecular mechanisms controlling legume autoregulation of nodulation.Annals of botany · 2011Review
- The ROOT DETERMINED NODULATION1 gene regulates nodule number in roots of Medicago truncatula and defines a highly conserved, uncharacterized plant gene family.Plant physiology · 2011Article
- How many E3 ubiquitin ligase are involved in the regulation of nodulation?Plant signaling & behavior · 2011Review
- Long-distance transport of signals during symbiosis: are nodule formation and mycorrhization autoregulated in a similar way?Plant signaling & behavior · 2011Review
Corrections and comments
- Commented on by
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The developmental program of nodulation is regulated systemically in leguminous host species. A mutant astray (Ljsym77) in Lotus japonicus has lost some sort of its ability to regulate this symtem, and shows enhanced and early nodulation. In the absence of rhizobia, this mutant exhibits characteristics associated with defects in light and gravity responses. These nonsymbiotic phenotypes of astray are very similar to those observed in photomorphogenic Arabidopsis mutant hy5. Based on this evidence, we predicted that astray might contain a mutation in the HY5 homologue of L. japonicus. The homologue, named LjBzf, encodes a basic leucine zipper protein in the C-terminal half that shows the highest level of identity with HY5 of all Arabidopsis proteins. It also encodes legume-characteristic combination of motifs, including a RING-finger motif and an acidic region in the N-terminal half. The astray phenotypes were cosegregated with LjBzf, and the failure to splice the intron was detected. Nonsymbiotic and symbiotic phenotypes of astray were complemented by introduction of CaMV35SLjBzf. It is noteworthy that although Arabidopsis hy5 showed an enhancement of lateral root initiation, Lotus astray showed an enhancement of nodule initiation but not of lateral root initiation. Legume-characteristic combination of motifs of ASTRAY may play specific roles in the regulation of nodule development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.