Evidence map›Paper›PMID 12396942›Full record

ArticleAtencion primaria2002

[At what care level are cyclo-oxygenase-2 inhibitors prescribed?].

M J Montero Fernández, F J Rodríguez Alcalá, N Valles Fernández, F López de Castro, M Esteban Tudela, B Cordero García

Abstract readComparative StudyEnglish Abstract
In one paragraph

Article in Atencion primaria, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M J Montero FernándezFarmacéutico. Gerencia de Atención Primaria de Toledo. España. mjmontero@sescam.org
F J Rodríguez Alcalá
N Valles Fernández
F López de Castro
M Esteban Tudela
B Cordero García

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo find the evolution in the billing of prescriptions for selective cyclooxygenase-2 (COX-2) inhibitors since they came on the market and to compare this evolution in primary care (PC) and specialist care (SC).Design. Cross-sectional, descriptive study.

settingToledo Health Area. Main measurements. Data were obtained from the System of Drug Information (SIFAR) to analyse the monthly turnover of NSAID prescriptions (M01A group in the official classification of medicines, including rofecoxib and celecoxib) issued by doctors in PC and SC between January 2000 and June 2001.

resultsIn our area during the study period, 583,558 NSAID packages were prescribed; 6.61% were COX-2 inhibitors, which represented 29.08% of NSAID expenditure. 98.23% of NSAID packages and 94.61% of COX-2 inhibitors were prescribed in PC. The use of COX-2 inhibitors in SC rose from 10.03% of the total NSAIDs in February 2000 to 29.79% in June 2001; whilst in PC it rose from 1.52% to 10.78%. Rofecoxib and celecoxib were third and fifth in the lists of most prescribed NSAIDs (number of packages) in SC, and ninth and twelfth in PC. In terms of cost of prescription, they were first and second in SC, and first and fourth in PC.

conclusionsCOX-2 inhibitors have become the main NSAIDs prescribed. The appearance of these drugs had a different impact on SC and PC doctors, with greater use of them and a more rapid introduction in SC.

Indexed as

Cross-Sectional StudiesCyclooxygenase 2Cyclooxygenase 2 InhibitorsCyclooxygenase InhibitorsDrug PrescriptionsHumansIsoenzymesMembrane ProteinsPractice Patterns, Physicians'Primary Health CareProstaglandin-Endoperoxide SynthasesSpainCyclooxygenase 2Cyclooxygenase 2 InhibitorsCyclooxygenase InhibitorsIsoenzymesMembrane ProteinsProstaglandin-Endoperoxide SynthasesPTGS2 protein, human

Identifiers

PMID12396942
PMCPMC7676627

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