ArticleDigestive diseases and sciences2002
Long-term outcome of congenital intestinal pseudoobstruction.
Article in Digestive diseases and sciences, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Pediatric Intestinal Pseudo-Obstruction: Progress and Challenges.Frontiers in pediatrics · 2022Pooled it
- Familial megacystis microcolon intestinal hypoperistalsis syndrome: a systematic review.Pediatric surgery international · 2013Pooled it
- Review of nutrition management of pediatric intestinal pseudo-obstruction.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Review
- Long-Term Outcomes and Clinical Course of Pediatric Intestinal Pseudo-Obstruction: A Retrospective Single-Center Cohort Study.Journal of clinical medicine · 2026Article
- Article
- International Forum on Visceral Myopathy 2024: Advances in the Knowledge of the Disease.Neurogastroenterology and motility · 2026Review
- Clinical, manometric, genetic, and histologic associations in pediatric intestinal pseudo-obstruction: A case series.Journal of pediatric gastroenterology and nutrition · 2026Article
- Incidence, diagnostics, therapeutic management and outcomes of paediatric intestinal pseudo-obstruction in the Netherlands: A 20-year retrospective cohort study.Journal of pediatric gastroenterology and nutrition · 2025Observational
- A single-center experience of home parenteral nutrition for pediatric intestinal failure.Frontiers in pediatrics · 2025Article
- Pediatric Chronic Intestinal Failure: Something Moving?Nutrients · 2024Review
- Dilated gut conditions: diagnosis and management.Clinical medicine (London, England) · 2023Review
- Natural History of Chronic Intestinal Pseudo-obstruction and Need for Palliative Care.Journal of neurogastroenterology and motility · 2023Article
- Pediatric Intestinal Pseudo-Obstruction: An International Survey on Diagnostic and Management Strategies in the European Reference Network for Rare Inherited and Congenital Anomalies Intestinal Failure Teams.Journal of pediatric gastroenterology and nutrition · 2023Article
- Paediatric intestinal pseudo-obstruction: a scoping review.European journal of pediatrics · 2022Article
- Chronic Intestinal Pseudo-Obstruction: Is There a Connection with Gut Microbiota?Microorganisms · 2021Review
- A Novel Cohesinopathy Causing Chronic Intestinal Pseudo Obstruction in 2 Siblings and Literature Review.Journal of neurogastroenterology and motility · 2021Article
- Clinical Outcomes of Pediatric Chronic Intestinal Pseudo-Obstruction.Journal of clinical medicine · 2021Article
- Radiological evaluation of a case of chronic intestinal pseudo-obstruction (CIPO).Radiology case reports · 2021Article
- Latest developments in chronic intestinal pseudo-obstruction.World journal of clinical cases · 2020Review
- Pediatric Intestinal Pseudo-obstruction in the Era of Genetic Sequencing.Current gastroenterology reports · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We evaluated 85 children with congenital chronic intestinal pseudoobstruction (CIP) over the past 10 years. Twelve (14%) were born prematurely. One had a family history of CIP. Six had systemic diseases. Thirty-five (41%) had urinary bladder involvement. Manometric features were consistent with myopathy in 32, neuropathy in 48, and mixed disease in 5. Of 48 patients with neuropathy, 6 had urinary bladder involvement (12.5%) (P < 0.0001 vs myopathy), and 10 had malrotation (21%) (P = NS vs myopathy). Upon referral, 53 (62%) were dependent on partial or total parenteral nutrition (PN). At the time of chart review (median 25 months after evaluation), 22 patients had died, 14 of whom were on total PN, 13 of them died because of PN-related complications and 1 died of sepsis. Three others died of sepsis while on partial PN (P = 0.007 vs mortality in patients fed enterally) and five died after small bowel transplantation. In conclusion, in children with congenital CIP, the risk for prematurity is increased twofold, the majority of cases are sporadic, abnormal bladder function is more common in myopathic CIP, and complications related to parenteral nutrition are the main cause of death in children with CIP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.