ArticleJournal of virology2002
A reverse genetics approach for recovery of recombinant influenza B viruses entirely from cDNA.
Article in Journal of virology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 75 citations in OpenAlex.
- Next-generation vaccines for influenza B virus: advancements and challenges.Archives of virology · 2025Review
- Influenza neuraminidase mutations and resistance to neuraminidase inhibitors.Emerging microbes & infections · 2024Review
- Unlocking influenza B: exploring molecular biology and reverse genetics for epidemic control and vaccine innovation.Virology journal · 2024Review
- Highs and Lows in Calicivirus Reverse Genetics.Viruses · 2024Review
- The Potential of Cyclodextrins as Inhibitors for the BM2 Protein: An In Silico Investigation.Molecules (Basel, Switzerland) · 2024Article
- Segmented, Negative-Sense RNA Viruses of Humans: Genetic Systems and Experimental Uses of Reporter Strains.Annual review of virology · 2023Review
- Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases.Signal transduction and targeted therapy · 2023Review
- SARS-CoV-2, Covid-19, and the debunking of conspiracy theories.Reviews in medical virology · 2021Review
- Influenza Reverse Genetics-Historical Perspective.Cold Spring Harbor perspectives in medicine · 2021Review
- Reverse genetics for influenza B viruses and recent advances in vaccine development.Current opinion in virology · 2020Review
- Establishment of a Reverse Genetics System for Influenza D Virus.Journal of virology · 2020Article
- ANP32 Proteins Are Essential for Influenza Virus Replication in Human Cells.Journal of virology · 2019Article
- The Development and Use of Reporter Influenza B Viruses.Viruses · 2019Review
- Functional studies reveal the similarities and differences between AM2 and BM2 proton channels from influenza viruses.Biochimica et biophysica acta. Biomembranes · 2018Article
- Reverse Genetics Approaches for the Development of Influenza Vaccines.International journal of molecular sciences · 2016Review
- The BM2 protein of influenza B virus interacts with p53 and inhibits its transcriptional and apoptotic activities.Molecular and cellular biochemistry · 2015Article
- Article
- The N terminus of the influenza B virus nucleoprotein is essential for virus viability, nuclear localization, and optimal transcription and replication of the viral genome.Journal of virology · 2014Article
- Universal influenza B virus genomic amplification facilitates sequencing, diagnostics, and reverse genetics.Journal of clinical microbiology · 2014Article
- Activation and proton transport mechanism in influenza A M2 channel.Biophysical journal · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recovery of recombinant influenza A virus entirely from cDNA was recently described (9, 19). We adapted the technique for engineering influenza B virus and generated a mutant bearing an amino acid change E116G in the viral neuraminidase which was resistant in vitro to the neuraminidase inhibitor zanamivir. The method also facilitates rapid isolation of single-gene reassortants suitable as vaccine seeds and will aid further investigations of unique features of influenza B virus.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.