Trial reportBMJ (Clinical research ed.)2002
Implementing intensive control of blood glucose concentration and blood pressure in type 2 diabetes in England: cost analysis (UKPDS 63).
Trial report in BMJ (Clinical research ed.), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02556723 (Intravitreal Injections of Ziv-aflibercept for Macular Diseases), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intravitreal Injections of Ziv-aflibercept for Macular Diseases: Diabetic Macular Edema, Wet AMD and Macular Edema Secondary to Vein Occlusons
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Blood pressure control for diabetic retinopathy.The Cochrane database of systematic reviews · 2023Pooled it
- Blood pressure control for diabetic retinopathy.The Cochrane database of systematic reviews · 2015Pooled it
- Trial
- A randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edema.Ophthalmology · 2008Trial
- Cost effectiveness of self monitoring of blood glucose in patients with non-insulin treated type 2 diabetes: economic evaluation of data from the DiGEM trial.BMJ (Clinical research ed.) · 2008Trial
- A cluster randomised controlled trial of the effect of a treatment algorithm for hypertension in patients with type 2 diabetes.The British journal of general practice : the journal of the Royal College of General Practitioners · 2007Trial
- Pharmacoeconomic Aspects of Diabetes Mellitus: Outcomes and Analysis of Health Benefits Approach.Current diabetes reviews · 2024Review
- Older People With Type 2 Diabetes-Individualising Management With a Specialised Community Team (OPTIMISE): Perspectives of Participants on Care.Clinical diabetes : a publication of the American Diabetes Association · 2021Article
- Blood pressure and glucose control and the prevalence of albuminuria and left ventricular hypertrophy in patients with hypertension and diabetes.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Sleep respiratory disorders and clinical profile in patients with type 2 diabetes mellitus.International archives of otorhinolaryngology · 2015Article
- Health economic evaluation of type 2 diabetes mellitus: a clinical practice focused review.Clinical medicine insights. Endocrinology and diabetes · 2015Review
- Article
- Article
- Spectral-domain optical coherence tomography for macular edema.TheScientificWorldJournal · 2014Review
- Changes in quality of care and costs induced by implementation of a diabetes program in a social security entity of Argentina.ClinicoEconomics and outcomes research : CEOR · 2013Article
- Derivation, validation, and evaluation of a new QRISK model to estimate lifetime risk of cardiovascular disease: cohort study using QResearch database.BMJ (Clinical research ed.) · 2010Article
- Article
- Forecasting the future economic burden of current adolescent overweight: an estimate of the coronary heart disease policy model.American journal of public health · 2009Article
- Predicting risk of type 2 diabetes in England and Wales: prospective derivation and validation of QDScore.BMJ (Clinical research ed.) · 2009Article
- A cost effectiveness study of integrated care in health services delivery: a diabetes program in Australia.BMC health services research · 2008Article
Corrections and comments
- Commented on by
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo estimate the incremental cost of implementing policies for intensive control of blood glucose concentration and blood pressure for all patients with type 2 diabetes in England.
designExtrapolation of resource use and cost data derived from a randomised controlled trial.
settingGeneral practice, outpatient care, and inpatient care. POPULATION: Trial population with diagnosed type 2 diabetes in England extrapolated to the population of England.
main outcome measuresTotal costs based on use of healthcare resources including costs of management, treatment, and hospitalisation.
resultsThe incremental net annual cost of implementing intensive control of blood glucose and blood pressure to all people with diagnosed type 2 diabetes in England is estimated to be pound 100.5m ($156m; euro;159m), which is equivalent to less than 1% of the proposed additional annual expenditure on the NHS in 2001-5. This estimate varied in sensitivity analyses from pound 67m to pound 121m.
conclusionsPolicies to improve control of blood glucose and blood pressure of people with type 2 diabetes are effective in reducing complications associated with the disease and are also cost effective. The total cost represents a small fraction of the NHS's spending plans.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.