ReviewOncogene2002
Biologic damage resulting from exposure to tobacco smoke and from radon: implication for preventive interventions.
Review in Oncogene, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Radon exposure and risk of cerebrovascular disease: a systematic review and meta-analysis in occupational and general population studies.Environmental science and pollution research international · 2022Pooled it
- Assessing historical residential radon exposure using a glass-based surface trap method in low radon level areas: a pilot study.Journal of radiological protection : official journal of the Society for Radiological Protection · 2026Article
- Benchmarking progress in cause-specific cancers in China: a nationwide analysis of premature mortality from 1990 to 2023.The Lancet regional health. Western Pacific · 2026Article
- Comprehensive computational analysis via Adverse Outcome Pathways and Aggregate Exposure Pathways in exploring synergistic effects from radon and tobacco smoke on lung cancer.Frontiers in public health · 2025Article
- Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019.BMJ oncology · 2023Article
- Epstein-Barr Virus Infection in Lung Cancer: Insights and Perspectives.Pathogens (Basel, Switzerland) · 2022Review
- Global, regional, and national cancer incidence and death for 29 cancer groups in 2019 and trends analysis of the global cancer burden, 1990-2019.Journal of hematology & oncology · 2021Article
- Environmental/Occupational Exposure to Radon and Non-Pulmonary Neoplasm Risk: A Review of Epidemiologic Evidence.International journal of environmental research and public health · 2021Review
- Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer.ESMO open · 2020Review
- Is the presence of lung injury in COVID-19 an independent risk factor for secondary lung cancer?Medical hypotheses · 2020Article
- Identification of nine key genes by bioinformatics analysis for predicting poor prognosis in smoking-induced lung adenocarcinoma.Lung cancer management · 2020Article
- Residential Radon Exposure and Cigarette Smoking in Association with Lung Cancer: A Matched Case-Control Study in Korea.International journal of environmental research and public health · 2020Article
- Epidemiological Study of Lung Cancer Incidence in Lebanon.Medicina (Kaunas, Lithuania) · 2019Article
- The epidemiology of lung cancer.Translational lung cancer research · 2018Review
- Differential protein-coding gene and long noncoding RNA expression in smoking-related lung squamous cell carcinoma.Thoracic cancer · 2017Article
- Identification of feature genes for smoking-related lung adenocarcinoma based on gene expression profile data.OncoTargets and therapy · 2016Article
- TEGS-CN: A Statistical Method for Pathway Analysis of Genome-wide Copy Number Profile.Cancer informatics · 2014Article
- Lung cancer mortality and radon concentration in a chronically exposed neighborhood in Chihuahua, Mexico: a geospatial analysis.TheScientificWorldJournal · 2014Article
- Arsenic, asbestos and radon: emerging players in lung tumorigenesis.Environmental health : a global access science source · 2012Review
- Cigarette smoking increases copy number alterations in nonsmall-cell lung cancer.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Cigarette smoking and residential radon are, respectively, the first and second leading cause of lung cancer in the United States today. Of the approximately 157 000 lung deaths occurring in 2000, approximately 90% can be attributed to cigarette smoking and 30% of the lung cancer deaths among non-smokers can be attributed to residential radon exposure. Although dwarfed by cigarette related lung cancer, lung cancer among lifetime non-smokers is a leading cause of death in the United States, and many other countries, accounting for approximately 16 000 deaths per year in the US. Laboratory studies and epidemiological investigations, particularly those conducted in the past decade, are yielding evidence that tobacco smoke and radon may share important elements of lung cancer's pathologic mechanism(s). Lung cancer prevention among smokers, ex-smokers and lifetime nonsmokers can be enhanced as we learn more about the etiologic mechanism(s) of lung cancer resulting from these and other exposures including diet, non-malignant respiratory diseases, occupational exposures, and susceptibility-gene. In this article we review both laboratory and epidemiologic data that gives insight into the biologic damage done to the lung from these exposures.
Indexed as
Identifiers
12379879What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.