ReviewCurrent cardiology reports2002
Genetics, the environment, and lipid abnormalities.
Review in Current cardiology reports, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- LIPG SNPs, their haplotypes and gene-environment interactions on serum lipid levels.Lipids in health and disease · 2019Trial
- CETP genotype and changes in lipid levels in response to weight-loss diet intervention in the POUNDS LOST and DIRECT randomized trials.Journal of lipid research · 2015Trial
- Association between theBioscience reports · 2018Article
- Association ofInternational journal of clinical and experimental pathology · 2018Article
- Association between theOncotarget · 2017Article
- Association of the SPTLC3 rs364585 polymorphism and serum lipid profiles in two Chinese ethnic groups.Lipids in health and disease · 2017Article
- Association ofInternational journal of clinical and experimental pathology · 2017Article
- Association between the MARS rs6782181 polymorphism and serum lipid levels.International journal of clinical and experimental pathology · 2015Article
- Demonstrating reduced environmental and genetic diversity in human isolates by analysis of blood lipid levels.Croatian medical journal · 2006Article
- Pharmacogenetics of lipid diseases.Human genomics · 2004Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Plasma lipid levels have been identified as major risk factors for cardiovascular disease. Multiple behavioral and environmental factors are known to modulate their concentrations in the general population; however, there is dramatic individual variability in the association between risk factors and disease, as well as in the individual response to therapeutic intervention. These differences may be due to the interaction between genetic and nongenetic factors that are ultimately responsible for the individual disease risk and response to intervention. Great strides have been made to characterize the genes involved in the homeostasis of plasma lipoprotein levels and to identify polymorphisms that could contribute to an earlier and more precise individual risk assessment. Especially relevant has been the recent interest and progress on examining the interaction between a number of candidate genes and nongenetic factors, namely smoking, alcohol drinking, physical activity, and sex. The APOE locus continues to be the most thoroughly studied gene in this regard; however, other genes (ie, LPL, APOC3, ADH3) are showing promising results.
Indexed as
Identifiers
12379174What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.