Evidence map›Paper›PMID 12374842›Full record

ArticleJournal of bacteriology2002

The gene yjfQ encodes the repressor of the yjfR-X regulon (ula), which is involved in L-ascorbate metabolism in Escherichia coli.

Evangelina Campos, Juan Aguilar, Laura Baldoma, Josefa Badia

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Enterococcus faecalis grows on ascorbic acid.Applied and environmental microbiology · 2013
    Article
  4. Article
  5. Article
  6. Overproduction, crystallization and preliminary X-ray analysis of the putative L-ascorbate-6-phosphate lactonase UlaG from Escherichia coli.Acta crystallographica. Section F, Structural biology and crystallization communications · 2008
    Article
  7. Article
  8. The ascorbate transporter of Escherichia coli.Journal of bacteriology · 2003
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Evangelina CamposDepartment of Biochemistry, Faculty of Pharmacy, University of Barcelona, 08028 Barcelona, Spain.
Juan Aguilar
Laura Baldoma
Josefa Badia
Universitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in yjfQ allowed us to identify this gene as the regulator of the operon yjfS-X (ula operon), reported to be involved in L-ascorbate metabolism. Inactivation of this gene renders constitutive the expression of the ula operon, indicating that YjfQ acts as a repressor. We also demonstrate that this repressor regulates the nearby yjfR gene, which in this way constitutes a regulon with the ula operon.

Indexed as

Gene Expression Regulation, BacterialGene Expression Regulation, EnzymologicOperonAmino Acid SequenceAscorbic AcidBase SequenceEscherichia coli ProteinsMolecular Sequence DataRegulonRepressor ProteinsAscorbic AcidEscherichia coli ProteinsRepressor ProteinsYifQ protein, E coli

Identifiers

PMID12374842
PMCPMC135402
OpenAlexW2171972144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.