Evidence map›Paper›PMID 12369616›Full record

ArticlePlant molecular biology2002

Molecular analysis of de novo pyrimidine synthesis in solanaceous species.

Norbert Giermann, Michael Schröder, Tina Ritter, Rita Zrenner

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Plant molecular biology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Frontiers in microbiology · 2019
    Article
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Norbert GiermannBotanisches Institut, Ruprecht-Karls-Universität Heidelberg, Germany.
Michael Schröder
Tina Ritter
Rita Zrenner
Heidelberg University · DEMax Planck Institute of Molecular Plant Physiology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The de novo synthesis of pyrimidine nucleotides in plants has been analysed on a molecular level with special focus on cDNA cloning and structure analysis of all genes involved and their expression pattern during development. The exhaustive cloning of all cDNAs resulted from screening with heterologous cDNAs or by using complementation strategies with Escherichia coli mutants and subsequent enzyme activity measurements. Southern hybridization and comparison with the Arabidopsis genome reveals plant specific aspects and a simple genomic organization of pyrimidine synthesis in plants, which is superimposed by the postulated, complex subcellular compartmentalization. Northern hybridization evinces coordinated expression of all genes under developmental control during tobacco leaf growth.

Indexed as

Oxidoreductases Acting on CH-CH Group DonorsArabidopsisAspartate CarbamoyltransferaseBlotting, NorthernCarbamoyl-Phosphate Synthase (Ammonia)Cloning, MolecularDihydroorotate DehydrogenaseDNA, ComplementaryDNA, PlantEscherichia coliGene Expression Regulation, DevelopmentalGene Expression Regulation, EnzymologicGene Expression Regulation, PlantGenesGenetic Complementation TestGenome, PlantAspartate CarbamoyltransferaseCarbamoyl-Phosphate Synthase (Ammonia)Dihydroorotate DehydrogenaseDNA, ComplementaryDNA, PlantOxidoreductasesOxidoreductases Acting on CH-CH Group DonorspyrimidinePyrimidinesRNA, Messenger

Identifiers

PMID12369616
OpenAlexW1532766121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.