Evidence map›Paper›PMID 12368869›Full record

ArticleNature2002

Sequence of Plasmodium falciparum chromosome 12.

Richard W Hyman, Eula Fung, Aaron Conway, Omar Kurdi, Jennifer Mao, Molly Miranda, Brian Nakao, Don Rowley, Tomoaki Tamaki, Fawn Wang and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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  3. Article
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  10. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Richard W HymanStanford Genome Technology Center, 855 California Avenue, Palo Alto, California 94304, USA. hyman@sequence.stanford.edu
Eula Fung
Aaron Conway
Omar Kurdi
Jennifer Mao
Molly Miranda
Brian Nakao
Don Rowley
Tomoaki Tamaki
Fawn Wang
Ronald W Davis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human malaria parasite Plasmodium falciparum is responsible for the death of more than a million people every year. To stimulate basic research on the disease, and to promote the development of effective drugs and vaccines against the parasite, the complete genome of P. falciparum clone 3D7 has been sequenced, using a chromosome-by-chromosome shotgun strategy. Here we report the nucleotide sequence of the third largest of the parasite's 14 chromosomes, chromosome 12, which comprises about 10% of the 23-megabase genome. As the most (A + T)-rich (80.6%) genome sequenced to date, the P. falciparum genome presented severe problems during the assembly of primary sequence reads. We discuss the methodology that yielded a finished and fully contiguous sequence for chromosome 12. The biological implications of the sequence data are more thoroughly discussed in an accompanying Article (ref. 3).

Indexed as

DNA, ProtozoanAnimalsChromosomesChromosomes, Artificial, YeastGenome, ProtozoanHumansPlasmodium falciparumProteomeProtozoan ProteinsSequence Analysis, DNADNA, ProtozoanProteomeProtozoan Proteins

Identifiers

PMID12368869

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.