ArticleThe Plant cell2002
A tumor suppressor homolog, AtPTEN1, is essential for pollen development in Arabidopsis.
Article in The Plant cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed, 147 citations in OpenAlex.
- Article
- Emerging Functions of Protein Tyrosine Phosphatases in Plants.International journal of molecular sciences · 2024Review
- HSF and Hsp Gene Families in sunflower: a comprehensive genome-wide determination survey and expression patterns under abiotic stress conditions.Protoplasma · 2023Article
- Pistachio genomes provide insights into nut tree domestication and ZW sex chromosome evolution.Plant communications · 2023Article
- Identification ofInternational journal of molecular sciences · 2023Article
- Integrated transcriptomic and proteomic analysis of a cytoplasmic male sterility line and associated maintainer line in soybean.Frontiers in plant science · 2023Article
- Importance of Tyrosine Phosphorylation in Hormone-Regulated Plant Growth and Development.International journal of molecular sciences · 2022Review
- AtPFA-DSP5 interacts with MPK3/MPK6 and negatively regulates plant salt responses.Plant signaling & behavior · 2021Article
- Comparative transcriptomic analysis reveals conserved programmes underpinning organogenesis and reproduction in land plants.Nature plants · 2021Article
- Importance of tyrosine phosphorylation for transmembrane signaling in plants.The Biochemical journal · 2021Review
- The Function of Inositol Phosphatases in Plant Tolerance to Abiotic Stress.International journal of molecular sciences · 2019Review
- Deletion ofJournal of fungi (Basel, Switzerland) · 2018Article
- Modulation of Auxin Levels in Pollen Grains Affects Stamen Development and Anther Dehiscence inInternational journal of molecular sciences · 2018Article
- Male functions and malfunctions: the impact of phosphoinositides on pollen development and pollen tube growth.Plant reproduction · 2016Review
- Phosphatase and Tensin Homolog Is a Growth Repressor of Both Rhizoid and Gametophore Development in the Moss Physcomitrella patens.Plant physiology · 2015Article
- Role of Protein Tyrosine Phosphatases in Plants.Current genomics · 2015Article
- Suppression of ASKβ (AtSK32), a Clade III Arabidopsis GSK3, Leads to the Pollen Defect during Late Pollen Development.Molecules and cells · 2015Article
- FlowerNet: a gene expression correlation network for anther and pollen development.Plant physiology · 2015Article
- AtDsPTP1 acts as a negative regulator in osmotic stress signalling during Arabidopsis seed germination and seedling establishment.Journal of experimental botany · 2015Article
- Development of molecular markers for genetic male sterility inMolecular breeding : new strategies in plant improvement · 2015Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although it is well known that Tyr phosphatases play a critical role in signal transduction in animal cells, little is understood of the functional significance of Tyr phosphatases in higher plants. Here, we describe the functional analysis of an Arabidopsis gene (AtPTEN1) that encodes a Tyr phosphatase closely related to PTEN, a tumor suppressor in animals. The recombinant AtPTEN1 protein, like its homologs in animals, is an active phosphatase that dephosphorylates phosphotyrosine and phosphatidylinositol substrates. RNA gel blot analysis and examination of promoter-reporter constructs in transgenic Arabidopsis plants revealed that the AtPTEN1 gene is expressed exclusively in pollen grains during the late stage of development. Suppression of AtPTEN1 gene expression by RNA interference caused pollen cell death after mitosis. We conclude that AtPTEN1 is a pollen-specific phosphatase and is essential for pollen development.
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