Evidence map›Paper›PMID 12368363›Full record

ArticleJournal of virology2002

Regions of mouse mammary tumor virus superantigen involved in interaction with the major histocompatibility complex class II I-A molecule.

Susanne Wirth, Annelyse Vessaz, Claude Krummenacher, Frédéric Baribaud, Hans Acha-Orbea, Heidi Diggelmann

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Susanne WirthInstitute of Microbiology, University of Lausanne, CH-1011 Lausanne, Switzerland. Susanne.Wirth-dulex@chuv.hospvd.ch
Annelyse Vessaz
Claude Krummenacher
Frédéric Baribaud
Hans Acha-Orbea
Heidi Diggelmann
Czech Academy of Sciences, Institute of Microbiology · CZUniversity of Lausanne · CHLudwig Cancer Research · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To study the major histocompatibility complex class II I-E dependence of mouse mammary tumor virus (MMTV) superantigens, we constructed hybrids between the I-E-dependent MMTV(GR) and the I-E-independent mtv-7 superantigens and tested them in vivo. Our results suggest that, although the C-terminal third mediates I-A interaction, additional binding sites are located elsewhere in the superantigen.

Indexed as

Amino Acid SequenceAnimalsAntigens, ViralCD4-Positive T-LymphocytesCell LineEpitopes, T-LymphocyteHistocompatibility Antigens Class IIMammary Tumor Virus, MouseMembrane GlycoproteinsMiceMice, Inbred BALB CMice, Inbred C57BLMolecular Sequence DataReceptors, Antigen, T-Cell, alpha-betaRecombinant Fusion ProteinsSuperantigensAntigens, ViralEpitopes, T-LymphocyteGR protein, mouse mammary tumor virusHistocompatibility Antigens Class III-E-antigenMembrane GlycoproteinsMtv-7 superantigen, Mouse mammary tumor virusReceptors, Antigen, T-Cell, alpha-betaRecombinant Fusion ProteinsSuperantigens

Identifiers

PMID12368363
PMCPMC136634
OpenAlexW2123849562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.