ArticleGenome research2002
Mosaic organization of orthologous sequences in grass genomes.
Article in Genome research, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Who cites it
68 citing papers in PubMed.
- Major impacts of widespread structural variation on sorghum.Genome research · 2024Article
- The regulation of zein biosynthesis in maize endosperm.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Review
- Genomic resources for gene discovery, functional genome annotation, and evolutionary studies of maize and its close relatives.Genetics · 2013Article
- Recent insertion of a 52-kb mitochondrial DNA segment in the wheat lineage.Functional & integrative genomics · 2011Article
- QTL for fibre-related traits in grain × sweet sorghum as a tool for the enhancement of sorghum as a biomass crop.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2011Article
- The amplification and evolution of orthologous 22-kDa α-prolamin tandemly arrayed genes in coix, sorghum and maize genomes.Plant molecular biology · 2010Article
- Ancestral grass karyotype reconstruction unravels new mechanisms of genome shuffling as a source of plant evolution.Genome research · 2010Article
- Amplification of prolamin storage protein genes in different subfamilies of the Poaceae.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2009Article
- Reconstruction of monocotelydoneous proto-chromosomes reveals faster evolution in plants than in animals.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- The fractionated orthology of Bs2 and Rx/Gpa2 supports shared synteny of disease resistance in the Solanaceae.Genetics · 2009Article
- Change of gene structure and function by non-homologous end-joining, homologous recombination, and transposition of DNA.PLoS genetics · 2009Article
- Structural characterization of Brachypodium genome and its syntenic relationship with rice and wheat.Plant molecular biology · 2009Article
- The 172-kb genomic DNA region of the O. rufipogon yld1.1 locus: comparative sequence analysis with O. sativa ssp. japonica and O. sativa ssp. indica.Functional & integrative genomics · 2009Article
- Comparative genomic analysis of C4 photosynthetic pathway evolution in grasses.Genome biology · 2009Article
- Organization of the prolamin gene family provides insight into the evolution of the maize genome and gene duplications in grass species.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Sequencing and comparative analysis of a conserved syntenic segment in the Solanaceae.Genetics · 2008Article
- Development of genic-microsatellite markers for sorghum staygreen QTL using a comparative genomic approach with rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2008Article
- Contrasted microcolinearity and gene evolution within a homoeologous region of wheat and barley species.Journal of molecular evolution · 2008Article
- Article
- Analysis of EST sequences suggests recent origin of allotetraploid colonial and creeping bentgrasses.Molecular genetics and genomics : MGG · 2007Article
8 more citing papers are in PubMed but not listed here.
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3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although comparative genetic mapping studies show extensive genome conservation among grasses, recent data provide many exceptions to gene collinearity at the DNA sequence level. Rice, sorghum, and maize are closely related grass species, once sharing a common ancestor. Because they diverged at different times during evolution, they provide an excellent model to investigate sequence divergence. We isolated, sequenced, and compared orthologous regions from two rice subspecies, sorghum, and maize to investigate the nature of their sequence differences. This study represents the most extensive sequence comparison among grasses, including the largest contiguous genomic sequences from sorghum (425 kb) and maize (435 kb) to date. Our results reveal a mosaic organization of the orthologous regions, with conserved sequences interspersed with nonconserved sequences. Gene amplification, gene movement, and retrotransposition account for the majority of the nonconserved sequences. Our analysis also shows that gene amplification is frequently linked with gene movement. Analyzing an additional 2.9 Mb of genomic sequence from rice not only corroborates our observations, but also suggests that a significant portion of grass genomes may consist of paralogous sequences derived from gene amplification. We propose that sequence divergence started from hotspots along chromosomes and expanded by accumulating small-scale genomic changes during evolution.
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