Trial reportJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Transient postischemic stunning evaluation by stress gated Tl-201 SPECT myocardial imaging: Effect on systolic left ventricular function.
Trial report in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
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Who cites it
12 citing papers in PubMed.
- Relationship of transient ischemic dilation in dipyridamole myocardial perfusion imaging and stress-induced changes of functional parameters evaluated by Tl-201 gated SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyTrial
- Impact of early post-stressThe international journal of cardiovascular imaging · 2021Article
- Gated SPECT in assessment of regional and global left ventricular function: an update.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Review
- Post-stress left ventricular ejection fraction drop in patients with diabetes: a gated myocardial perfusion imaging study.BMC cardiovascular disorders · 2013Article
- Comparative assessment of rest and post-stress left ventricular volumes and left ventricular ejection fraction on gated myocardial perfusion imaging (MPI) and echocardiography in patients with transient ischaemic dilation on adenosine MPI: myocardial stunning or subendocardial hypoperfusion?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2012Article
- Bromocriptine enhances the uptake of (99m)Tc-MIBI in patients with hepatocellular carcinoma.Journal of biomedical research · 2012Article
- Serial assessment of left ventricular function in various patient groups with Tl-201 gated myocardial perfusion SPECT.Radiation medicine · 2007Article
- Transient ischemic dilatation of the left ventricle with severe post stress left ventricular dysfunction in the setting of severe aortic stenosis and normal coronary arteries.The international journal of cardiovascular imaging · 2006Article
- Correlation of expression of multidrug resistance protein and messenger RNA with 99mTc-methoxyisobutyl isonitrile (MIBI) imaging in patients with hepatocellular carcinoma.World journal of gastroenterology · 2004Article
- A historical perspective on measurement of ventricular function with scintigraphic techniques: Part II--Ventricular function with gated techniques for blood pool and perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyArticle
- Worsening of left ventricular ejection fraction induced by dipyridamole on Tl-201 gated myocardial perfusion imaging predicts significant coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyArticle
- Gated SPECT in assessment of regional and global left ventricular function: major tool of modern nuclear imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTransient postischemic stunning (TIS) has been reported in images obtained (1/2) to 1 hour after stress with technetium 99m tracers but has not been investigated in images obtained shortly after stress with thallium 201. We also quantified the global extent and severity of TIS, which has not been done previously. METHODS AND
resultsWe evaluated 82 patients with either treadmill or dobutamine stress Tl-201 myocardial perfusion imaging. Images were semiquantitatively examined with a 20-segment model. The extent and severity of myocardial ischemia and TIS were assessed by the summed difference score from the early and delayed scores of perfusion, wall motion (WM), and wall thickening (WT). The mean left ventricular ejection fraction (LVEF) was significantly lower in early images than in delayed images in patients with ischemia (P <.01), TIS by WM (P <.001), and TIS by WT (P <.001), and the LVEF difference was more significantly different as the summed difference score of perfusion, WM, or WT increased. No significant LVEF difference was seen in patients with ischemia who did not have TIS.
conclusionsIn stress gated Tl-201 single photon emission computed tomography myocardial perfusion imaging, early TIS is frequently seen in patients with ischemia and is equivalently detected by WM and WT assessments. Significant exercise-induced transient left ventricular global dysfunction is associated with more severe and extensive ischemia and can be predicted by the measurement of the extent and severity of TIS from the same images.
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