ArticleThe EMBO journal2002
Mammalian Rcd1 is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation.
Article in The EMBO journal, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
- Structure and function of molecular machines involved in deadenylation-dependent 5'-3' mRNA degradation.Frontiers in genetics · 2023Review
- Quantitative analysis of sensitivity to a Wnt3a gradient in determination of the pole-to-pole axis of mitotic cells by using a microfluidic device.FEBS open bio · 2018Article
- Metazoan evolution of the armadillo repeat superfamily.Cellular and molecular life sciences : CMLS · 2017Article
- Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma.Oncotarget · 2015Article
- Differential transcriptome analysis reveals insight into monosymmetric corolla development of the crucifer Iberis amara.BMC plant biology · 2014Article
- Assessing uncertainty in model parameters based on sparse and noisy experimental data.Frontiers in physiology · 2014Article
- Multifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.Frontiers in genetics · 2014Review
- Looking beyond the Wnt pathway for the deep nature of β-catenin.EMBO reports · 2013Review
- Reshaping of global gene expression networks and sex-biased gene expression by integration of a young gene.The EMBO journal · 2012Article
- Functional cDNA expression cloning: pushing it to the limit.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2012Review
- The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.Molecular biology of the cell · 2011Article
- Article
- The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation.Molecular biology of the cell · 2009Article
- ARS2 is a conserved eukaryotic gene essential for early mammalian development.Molecular and cellular biology · 2008Article
- Atomic model of human Rcd-1 reveals an armadillo-like-repeat protein with in vitro nucleic acid binding properties.Protein science : a publication of the Protein Society · 2007Article
- Quantitative analysis of cell-type specific gene expression in the green alga Volvox carteri.BMC genomics · 2006Article
- Involvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complex.The Biochemical journal · 2006Article
- Systematic spatial analysis of gene expression during wheat caryopsis development.The Plant cell · 2005Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rcd1, initially identified as a factor essential for the commitment to nitrogen starvation-invoked differentiation in fission yeast, is one of the most conserved proteins found across eukaryotes, and its mammalian homolog is expressed in a variety of differentiating tissues. Here we show that mammalian Rcd1 is a novel transcriptional cofactor and is critically involved in the commitment step in the retinoic acid-induced differentiation of F9 mouse teratocarcinoma cells, at least in part, via forming complexes with retinoic acid receptor and activation transcription factor-2 (ATF-2). In addition, antisense oligonucleotide treatment of embryonic mouse lung explants suggests that Rcd1 also plays a role in retinoic acid-controlled lung development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.