Evidence map›Paper›PMID 12354902›Full record

ArticleJournal of clinical microbiology2002

Stability of human immunodeficiency virus type 1 RNA in cerebrospinal fluid determined with the AMPLICOR HIV-1 MONITOR test, version 1.5 (ultrasensitive).

Elyse J Singer, H Aaron Aronow, Shing-Yi Lee, Charles H Hinkin, Tadd Lazarus

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elyse J SingerDepartment of Neurology, School of Medicine, University of California at Los Angeles, 11645 Wilshire Boulevard, Suite 770, Los Angeles, CA 90025, USA. esinger@ucla.edu
H Aaron Aronow
Shing-Yi Lee
Charles H Hinkin
Tadd Lazarus

Funding

National Neurological AIDS Bank (NNAB)R24NS038841 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SINGER, ELYSE J · 1998 to 2007
$12.0M
NINDS NIH HHS NS-38841NINDS NIH HHS R24 NS038841
6 · The paper itself

Abstract

We evaluated the effects of time, temperature, freezing, and thawing on the cerebrospinal fluid viral load by using the Roche AMPLICOR HIV-1 MONITOR test, version 1.5 (ultrasensitive). While a statistically significant decrease from the baseline was observed at 24 h, but not at 6 or 12 h, and with one freeze-thaw cycle, all changes were within the range of intra-assay variability.

Indexed as

HIV-1HumansReagent Kits, DiagnosticRNA StabilityRNA, ViralViral LoadReagent Kits, DiagnosticRNA, Viral

Identifiers

PMID12354902
PMCPMC130842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.