ArticleJournal of clinical microbiology2002
Identification of Candida glabrata by a 30-second trehalase test.
Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Biosynthesis of Silver Nanoparticles from OropharyngealNanomaterials (Basel, Switzerland) · 2018Article
- Diversity and antifungal susceptibility of Norwegian Candida glabrata clinical isolates.Journal of oral microbiology · 2016Article
- Biology of the pathogenic yeast Candida glabrata.Folia microbiologica · 2006Review
- Multicenter evaluation of a Candida albicans peptide nucleic acid fluorescent in situ hybridization probe for characterization of yeast isolates from blood cultures.Journal of clinical microbiology · 2005Article
- Comparison of a new commercial test, GLABRATA RTT, with a dipstick test for rapid identification of Candida glabrata.Journal of clinical microbiology · 2005Article
- Routine use of a commercial test, GLABRATA RTT, for rapid identification of Candida glabrata in six laboratories.Journal of clinical microbiology · 2004Article
- Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-like transcription factor.Antimicrobial agents and chemotherapy · 2004Article
- Comparison of VITEK 2 with ITS2-fragment length polymorphism analysis for identification of yeast species.Journal of clinical microbiology · 2004Article
- Routine use of a one minute trehalase and maltase test for the identification of Candida glabrata in four laboratories.Journal of clinical pathology · 2003Article
- Rapid identification of Candida glabrata with a new commercial test, GLABRATA RTT.Journal of clinical microbiology · 2003Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid (30-s) trehalase tests done with material from colonies of 482 yeasts suspended in a drop of trehalose solution on a commercially supplied glucose test strip were positive for 225 (99.1%) of 227 Candida glabrata isolates grown on either of two differential media, Candida ID medium or CandiSelect medium. The test was positive for only 3 (1.2%) and 12 (4.7%) of 255 isolates of other medically important yeast species grown on the same two media, respectively. A rapid maltase test done with a subset of 255 yeast isolates was negative for all but 1 of 64 trehalase-positive C. glabrata isolates, raising the specificity of the rapid testing for C. glabrata to 98.4 to 100%, depending on the isolation medium used. Rapid trehalase and maltase tests done independently in two laboratories with 217 yeast isolates showed sensitivities of 96.0 to 98.0% and specificities of 98.2 to 99.4% for identification of C. glabrata from colonies grown on Candida ID medium. The specificity was much lower because of frequent false-positive trehalose test results when the source of colonies was Sabouraud agar formulated with 4% glucose. We conclude that direct recognition of C. albicans as blue colonies on Candida ID isolation medium coupled with the performance of the 30-s trehalase and maltase tests for C. glabrata among the white colonies on this medium will allow the rapid presumptive identification of the two yeast species most commonly encountered in clinical samples.
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