ArticleJournal of clinical pathology2002
Comparison of API20C with molecular identification of Candida spp isolated from bloodstream infections.
Article in Journal of clinical pathology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- MALDI-TOF MS Overcomes Misidentification of the Uncommon Human Pathogen Candida famata by Routine Phenotypic Identification Methods.Current microbiology · 2021Article
- Antifungal resistance to fluconazole and echinocandins is not emerging in yeast isolates causing fungemia in a Spanish tertiary care center.Antimicrobial agents and chemotherapy · 2014Article
- Misidentification of Candida guilliermondii as C. famata among strains isolated from blood cultures by the VITEK 2 system.BioMed research international · 2014Article
- Paradoxical effect of caspofungin against Candida bloodstream isolates is mediated by multiple pathways but eliminated in human serum.Antimicrobial agents and chemotherapy · 2011Article
- High-throughput identification and quantification of Candida species using high resolution derivative melt analysis of panfungal amplicons.The Journal of molecular diagnostics : JMD · 2010Article
- Patients with long-term oral carriage harbor high-persister mutants of Candida albicans.Antimicrobial agents and chemotherapy · 2010Article
- Use of a panfungal PCR assay for detection of fungal pathogens in a commercial blood culture system.Journal of clinical microbiology · 2004Article
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Authors and funding
8 authors.
Funding
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Abstract
A study was carried out to compare the API20C technology with polymerase chain reaction amplification and direct sequencing of the short internal transcribed spacer region 2 (ITS2) for the identification of 58 isolates of invasive candida species obtained from patients with bloodstream infections over the seven year period 1994 to 2000. Overall, there was only one disagreement between the phenotypic and genotypic identification, where the API scheme identified the isolate as C albicans but the molecular method identified it as C dubliniensis. This study demonstrated that the API20C method is useful in the identification of Candida spp isolated from blood culture and that molecular methods do not enhance identifications made using the API20C scheme. However, for correct reporting of C dubliniensis, an emerging bloodborne pathogen, it is recommended that all isolates identified as C albicans by the API20C scheme are further examined phenotypically and/or genotypically.
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