ReviewCurrent oncology reports2002
Interferons as antiangiogenic agents.
Review in Current oncology reports, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 75 citations in OpenAlex.
- Interferon-alpha therapy for refractory kaposiform hemangioendothelioma: a single-center experience.Scientific reports · 2016Trial
- Role of the TLR signaling pathway in the pathogenesis of glioblastoma multiforme with an emphasis on immunotherapy.Biochemistry and biophysics reports · 2025Review
- The Immunotherapeutic Role of Type I and III Interferons in Melanoma and Non-Melanoma Skin Cancers.Life (Basel, Switzerland) · 2023Review
- Injectable biomaterial shuttles for cell therapy in stroke.Brain research bulletin · 2021Review
- Tryptophanyl-tRNA Synthetase as a Potential Therapeutic Target.International journal of molecular sciences · 2021Review
- Up-regulation of indoleamine 2,3-dioxygenase 1 (IDO1) expression and catalytic activity is associated with immunosuppression and poor prognosis in penile squamous cell carcinoma patients.Cancer communications (London, England) · 2020Article
- Production of biologically active feline interferon beta in insect larvae using a recombinant baculovirus.3 Biotech · 2018Article
- Review
- Differential growth and responsiveness to cancer therapy of tumor cells in different environments.Clinical & experimental metastasis · 2016Article
- Strategies and developments of immunotherapies in osteosarcoma.Oncology letters · 2016Article
- Pivotal role for decorin in angiogenesis.Matrix biology : journal of the International Society for Matrix Biology · 2015Review
- Treatment of alarming head and neck infantile hemangiomas with interferon-α2a: a clinical study in eleven consecutive patients.Drug design, development and therapy · 2015Article
- Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling.Nature chemical biology · 2012Article
- Endothelial progenitor cells: a new player in lupus?Arthritis research & therapy · 2012Review
- Article
- Possible angiogenic roles for claudin-4 in ovarian cancer.Cancer biology & therapy · 2009Article
- Phase I analysis of BCNU-impregnated biodegradable polymer wafers followed by systemic interferon alfa-2b in adults with recurrent glioblastoma multiforme.Journal of neuro-oncology · 2008Article
- Regulation of apoptosis by type III interferons.Cell proliferation · 2008Article
- Interferons at age 50: past, current and future impact on biomedicine.Nature reviews. Drug discovery · 2007Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interferons (IFNs), pleiotropic cytokines that regulate antiviral, antitumor, apoptotic, and cellular immune responses, were the first endogenous antiangiogenic regulators identified. In a species-specific manner, IFNs inhibit secretion of such angiogenic factors as basic fibroblast growth factor from tumor cells. The antiangiogenic activity of IFNs is enhanced when they are combined with other antiangiogenic agents, such as tamoxifen and thalidomide.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.