ArticleGenetics2002
The effect of population history on the lengths of ancestral chromosome segments.
Article in Genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 79 citations in OpenAlex.
- Genomic architecture of non-nominal offspring risk in a simulated composite cattle breed.Genetics, selection, evolution : GSE · 2026Article
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- Analytical expectations for ancestry junction accumulation in admixed genomes.bioRxiv : the preprint server for biology · 2025Article
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- Estimating the time since admixture from phased and unphased molecular data.Molecular ecology resources · 2022Article
- Demographic history shapes genomic ancestry in hybrid zones.Ecology and evolution · 2021Article
- Space is the Place: Effects of Continuous Spatial Structure on Analysis of Population Genetic Data.Genetics · 2020Article
- Signatures of hybridization and speciation in genomic patterns of ancestry.Evolution; international journal of organic evolution · 2018Article
- The breakdown of genomic ancestry blocks in hybrid lineages given a finite number of recombination sites.Evolution; international journal of organic evolution · 2018Article
- Adaptive introgression: a plant perspective.Biology letters · 2018Review
- What, if anything, are hybrids: enduring truths and challenges associated with population structure and gene flow.Evolutionary applications · 2016Article
- A Continuous Correlated Beta Process Model for Genetic Ancestry in Admixed Populations.PloS one · 2016Article
- Article
- The lengths of admixture tracts.Genetics · 2014Article
- Review
- The geography of recent genetic ancestry across Europe.PLoS biology · 2013Article
- PCAdmix: principal components-based assignment of ancestry along each chromosome in individuals with admixed ancestry from two or more populations.Human biology · 2012Article
- Accuracy and computational efficiency of a graphical modeling approach to linkage disequilibrium estimation.Statistical applications in genetics and molecular biology · 2011Article
- Assessment of SNP streak statistics using gene drop simulation with linkage disequilibrium.Genetic epidemiology · 2010Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An isolated population is a group of individuals who are descended from a founding population who lived some time ago. If the founding individuals are assumed to be noninbred and unrelated, a chromosome sampled from the population can be represented as a mosaic of segments of the original ancestral types. A population in which chromosomes are made up of a few long segments will exhibit linkage disequilibrium due to founder effect over longer distances than a population in which the chromosomes are made up of many short segments. We study the length of intact ancestral segments by obtaining the expected number of junctions (points where DNA of two distinct ancestral types meet) in a chromosome. Assuming random mating, we study analytically the effects of population age, growth patterns, and internal structure on the expected number of junctions in a chromosome. We demonstrate that the type of growth a population has experienced can influence the expected number of junctions, as can population subdivision. These effects are substantial only when population sizes are very small. We also develop an approximation to the variance of the number of junctions and show that the variance is large.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.