Evidence map›Paper›PMID 12242177›Full record

ArticleBMJ (Clinical research ed.)2002

Married couples' risk of same disease: cross sectional study.

Julia Hippisley-Cox, Carol Coupland, Mike Pringle, Nicola Crown, Vicky Hammersley

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in BMJ (Clinical research ed.), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 4 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 4 syntheses or guidelines pooled it, 179 citations in OpenAlex.

  1. Pooled it
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  3. Spousal concordance for hypertension: A meta-analysis of observational studies.Journal of clinical hypertension (Greenwich, Conn.) · 2017
    Pooled it
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  9. [Spousal correlations of blood lipid based on a family design].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
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  18. Human height: a model common complex trait.Annals of human biology · 2023
    Review
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Julia Hippisley-CoxDivision of General Practice, School of Community Health Sciences, University of Nottingham, Nottingham NG7 2RD. julia.hippisley-cox@nottingham.ac.uk
Carol Coupland
Mike Pringle
Nicola Crown
Vicky Hammersley
Bellingham Technical College · USUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether people whose marital partners have depression, diabetes, hypertension, ischaemic heart disease, stroke, hyperlipidaemia, peptic ulcer disease, or asthma or chronic obstructive pulmonary disease are at increased risk of the same disease.

designCross sectional study.

setting10 practices from the Trent Focus Collaborative Research Practice Network.

participants8386 married couples (16 772 individuals) from a population of 29 014 participants aged 30-74 years. OUTCOMES: Risk of disease in participants whose marital partner had that disease compared with those whose partner did not.

resultsAfter both partners' age, smoking, and obesity and which general practice they attend were adjusted for, participants whose marital partner had asthma, depression, hypertension, hyperlipidaemia, and peptic ulcer disease were at increased risk of having the same disease. The adjusted odds ratios were 1.69 (95% confidence interval 1.43 to 2.98) for asthma, 2.08 (1.71 to 2.54) for depression, 1.32 (1.04 to 1.67) for hypertension, 1.44 (1.19 to 1.75) for hyperlipidaemia, and 2.01 (1.48 to 2.73) for peptic ulcer disease.

conclusionPartners of people with specific diseases are at increased risk of the disease themselves-at least 70% increased risk for asthma, depression, and peptic ulcer disease. This implicates shared environmental causes in some diseases in addition to any genetic or distant exposure or shared behaviours with respect to seeking health care.

Indexed as

SpousesAdultAgedCardiovascular DiseasesCross-Sectional StudiesDepressive DisorderDiseaseDisease Transmission, InfectiousFemaleHumansHyperlipidemiasMaleMiddle AgedMultivariate AnalysisPeptic UlcerRespiratory Tract Diseases

Identifiers

PMID12242177
PMCPMC126307
OpenAlexW2141181766

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.